通过分子内曼尼希环化反应和N-亚磺酰基δ-氨基β-酮酯实现喹诺里西啶生物碱（-）-表桃金娘碱的不对称合成。
Asymmetric synthesis of the quinolizidine alkaloid (-)-epimyrtine with intramolecular Mannich cyclization and N-sulfinyl delta-amino beta-ketoesters.
作者信息
Davis Franklin A, Zhang Yulian, Anilkumar Gopinathan
机构信息
Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA.
出版信息
J Org Chem. 2003 Oct 17;68(21):8061-4. doi: 10.1021/jo030208d.
PMID:14535782
Abstract
A concise, six-step, enantioselective synthesis of (-)-epimyrtine employing the N-sulfinyl delta-amino beta-ketoester chiral building block is described.
摘要
描述了一种使用N-亚磺酰基δ-氨基β-酮酯手性砌块对（-）-表桃金娘烯醇进行简洁的六步对映选择性合成方法。
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