Comins Daniel L, Sahn James J
Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695-8204, USA.
Org Lett. 2005 Nov 10;7(23):5227-8. doi: 10.1021/ol052068v.
[reaction: see text] The ladybird alkaloid, (+)-hyperaspine, has been synthesized in a concise and highly stereoselective manner. The total synthesis was accomplished in six steps and 21% overall yield.
[反应:见正文] 瓢虫生物碱(+)-高刺桐碱已通过简洁且高度立体选择性的方式合成。该全合成以六步完成,总收率为21%。