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妇科手术中预防粘连的新观念。

New adhesion prevention concept in gynecological surgery.

作者信息

Mettler L, Audebert A, Lehmann-Willenbrock E, Jacobs V R, Schive K

机构信息

Department of Obstetrics and Gynecology, University of Kiel, Kiel, Germany.

出版信息

JSLS. 2003 Jul-Sep;7(3):207-9.

PMID:14558707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3113199/
Abstract

Postsurgical adhesion formation is a common but significant problem. This is the first clinical evaluation of a new barrier material designed to reduce or eliminate postsurgical adhesions. SprayGel can be delivered laparoscopically or via laparotomy to form a strongly adherent hydrogel film. In this multicenter study, we evaluated the safety and effectiveness of SprayGel absorbable adhesion barrier system in patients undergoing open or laparoscopic myomectomy procedures. Here, we discuss the results of our evaluation conducted at the University of Kiel and Polyclinic of Bordeaux, and assess some of the features of this novel adjunct to prevent formation of postsurgical adhesions.

摘要

术后粘连形成是一个常见但严重的问题。这是对一种旨在减少或消除术后粘连的新型屏障材料的首次临床评估。SprayGel可通过腹腔镜或开腹手术给药,以形成牢固附着的水凝胶膜。在这项多中心研究中,我们评估了SprayGel可吸收粘连屏障系统在接受开放性或腹腔镜子宫肌瘤切除术患者中的安全性和有效性。在此,我们讨论在基尔大学和波尔多综合医院进行的评估结果,并评估这种预防术后粘连形成的新型辅助材料的一些特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/7787ad6b47c5/jsls-7-3-207-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/3a2fbc90542e/jsls-7-3-207-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/8da82a8f5bf7/jsls-7-3-207-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/7787ad6b47c5/jsls-7-3-207-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/3a2fbc90542e/jsls-7-3-207-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/8da82a8f5bf7/jsls-7-3-207-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1eb/3113199/7787ad6b47c5/jsls-7-3-207-g03.jpg

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Notice of duplicate publication.重复发表声明。

本文引用的文献

1
Evaluation of the SprayGel adhesion barrier in the rat cecum abrasion and rabbit uterine horn adhesion models.在大鼠盲肠擦伤和兔子宫角粘连模型中对SprayGel粘连屏障的评估。
Fertil Steril. 2001 Feb;75(2):411-6. doi: 10.1016/s0015-0282(00)01677-0.
2
Correlation between endometriosis and pelvic pain.子宫内膜异位症与盆腔疼痛之间的相关性。
J Am Assoc Gynecol Laparosc. 1999 Nov;6(4):429-34. doi: 10.1016/s1074-3804(99)80006-1.
3
Adhesions after extensive gynecologic surgery: clinical significance, etiology, and prevention.广泛妇科手术后的粘连:临床意义、病因及预防
JSLS. 2004 Jan-Mar;8(1):99.
Am J Obstet Gynecol. 1994 May;170(5 Pt 1):1396-403. doi: 10.1016/s0002-9378(94)70170-9.
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Pathogenesis of adhesion formation/reformation: application to reproductive pelvic surgery.粘连形成/再形成的发病机制:在生殖盆腔手术中的应用
Microsurgery. 1987;8(2):103-7. doi: 10.1002/micr.1920080215.
5
The importance of periadnexal adhesions in tubal reconstructive surgery for infertility.附件周围粘连在输卵管重建手术治疗不孕症中的重要性。
Fertil Steril. 1979 Mar;31(3):296-300. doi: 10.1016/s0015-0282(16)43877-x.