肉鸡弯曲杆菌的抗菌药物耐药性：与生产类型及抗菌药物使用的关联
Antimicrobial resistance in Campylobacter from broilers: association with production type and antimicrobial use.
作者信息
Avrain Laetitia, Humbert Florence, L'Hospitalier Rolande, Sanders Pascal, Vernozy-Rozand Christine, Kempf Isabelle
机构信息
Unité de Mycoplasmologie-Bactériologie, Agence française de Sécurité Sanitaire des Aliments, BP 53, F-22440 Ploufragan, France.
出版信息
Vet Microbiol. 2003 Oct 30;96(3):267-76. doi: 10.1016/j.vetmic.2003.07.001.
The isolation and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli strains from broilers arriving in French slaughterhouses, were analysed according to production types (i.e. standard, export or free-range) and antimicrobial (i.e. coccidiostats, growth promoters or therapeutic agents) administration in flocks. Prevalence was 56.6% in standard, 51.3% in export and 80.0% in free-range broilers. Three hundred and ninety-three strains were identified. Two-thirds of the strains belonged to the species C. jejuni. The others were C. coli. Antimicrobial susceptibility testing was carried out for ampicillin, nalidixic acid, enrofloxacin, tetracycline, erythromycin and gentamicin according to a dilution method. The percentages of resistant strains were, 23, 25, 17, 57, 0.3 and 0% for C. jejuni and 29, 43, 40, 70, 31 and 0% for C. coli. Statistical analysis revealed significant difference in distribution of C. jejuni and C. coli and antimicrobial resistance according to production type or antimicrobial administration.
根据生产类型（即标准型、出口型或散养型）以及鸡群中抗菌药物（即抗球虫药、生长促进剂或治疗剂）的使用情况，对抵达法国屠宰场的肉鸡空肠弯曲菌和结肠弯曲菌菌株的分离情况及抗菌药物耐药性进行了分析。标准型肉鸡的患病率为56.6%，出口型为51.3%，散养型为80.0%。共鉴定出393株菌株。三分之二的菌株属于空肠弯曲菌，其余为结肠弯曲菌。根据稀释法对氨苄西林、萘啶酸、恩诺沙星、四环素、红霉素和庆大霉素进行了药敏试验。空肠弯曲菌耐药菌株的百分比分别为23%、25%、17%、57%、0.3%和0%，结肠弯曲菌分别为29%、43%、40%、70%、31%和0%。统计分析表明，空肠弯曲菌和结肠弯曲菌的分布以及抗菌药物耐药性根据生产类型或抗菌药物使用情况存在显著差异。
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