Anacleto Francisco E, Cifra Christina L, Elises Joel S
Section of Pediatric Nephrology, Department of Pediatrics, Philippine General Hospital Medical Center, Manila, Philippines 1000.
Pediatr Nephrol. 2003 Dec;18(12):1283-5. doi: 10.1007/s00467-003-1261-7. Epub 2003 Oct 15.
A 17-year-old Filipina primigravid developed acute renal failure secondary to hemolytic uremic syndrome (HUS) after undergoing emergency cesarean section for severe pre-eclampsia and abruptio placenta. She underwent hemodialysis with concurrent infusions of fresh-frozen plasma and packed red cells for 5 weeks. Renal biopsy revealed findings consistent with HUS with glomerular crescents. She received three doses of pulse methylprednisolone followed by oral prednisone. Renal function improved 5 weeks after the onset of HUS. The pathogenesis, differential diagnosis, and treatment options of postpartum HUS are discussed.
一名17岁的菲律宾初产妇，因重度子痫前期和胎盘早剥接受急诊剖宫产术后，继发溶血性尿毒症综合征（HUS），出现急性肾衰竭。她接受了5周的血液透析，同时输注新鲜冰冻血浆和浓缩红细胞。肾活检显示符合伴有肾小球新月体的HUS表现。她接受了三剂甲泼尼龙冲击治疗，随后口服泼尼松。HUS发病5周后肾功能改善。本文讨论了产后HUS的发病机制、鉴别诊断和治疗选择。
