Lamond N, Dorrian J, Roach G D, Burgess H J, Holmes A L, McCulloch K, Fletcher A, Dawson D
Centre for Sleep Research, University of South Australia, Woodville, Australia.
J Hum Ergol (Tokyo). 2001 Dec;30(1-2):137-42.
The current study investigated changes in night-time performance, daytime sleep, and circadian phase during a week of simulated shift work. Fifteen young subjects participated in an adaptation and baseline night sleep, directly followed by seven night shifts. Subjects slept from approximately 0800 hr until they naturally awoke. Polysomnographic data was collected for each sleep period. Saliva samples were collected at half hourly intervals, from 2000 hr to bedtime. Each night, performance was tested at hourly intervals. Analysis indicated that there was a significant increase in mean performance across the week. In general, sleep was not negatively affected. Rather, sleep quality appeared to improve across the week. However, total sleep time (TST) for each day sleep was slightly reduced from baseline, resulting in a small cumulative sleep debt of 3.53 (SD = 5.62) hours. Finally, the melatonin profile shifted across the week, resulting in a mean phase delay of 5.5 hours. These findings indicate that when sleep loss is minimized and a circadian phase shift occurs, adaptation of performance can occur during several consecutive night shifts.
当前研究调查了一周模拟轮班工作期间夜间表现、日间睡眠和昼夜节律相位的变化。15名年轻受试者参与了适应性和基线夜间睡眠，随后直接进行了七个夜班。受试者从大约08:00开始睡觉，直到自然醒来。每个睡眠时段均收集多导睡眠图数据。从20:00到就寝时间，每隔半小时采集一次唾液样本。每晚每隔一小时测试一次表现。分析表明，整周的平均表现有显著提高。总体而言，睡眠未受到负面影响。相反，睡眠质量似乎在整周有所改善。然而，每个日间睡眠的总睡眠时间（TST）比基线略有减少，导致累积睡眠债为3.53（标准差=5.62）小时。最后，褪黑素曲线在整周发生了变化，导致平均相位延迟5.5小时。这些发现表明，当睡眠缺失最小化且发生昼夜节律相位偏移时，连续几个夜班期间表现可以发生适应性变化。
