Babu B Ravindra, Keinicke Lise, Wengel Jesper
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1313-5. doi: 10.1081/NCN-120022954.
Four conformationally restricted bicyclic 2'-spiro nucleosides were synthesised and incorporated into oligonucleotides. These spiro nucleotides induced decreased duplex thermostabilities.
