Synthesis of 2'-spiro ribo- and arabinonucleosides.
作者信息
Babu B Ravindra, Keinicke Lise, Wengel Jesper
机构信息
Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1313-5. doi: 10.1081/NCN-120022954.
PMID:14565407
Abstract
Four conformationally restricted bicyclic 2'-spiro nucleosides were synthesised and incorporated into oligonucleotides. These spiro nucleotides induced decreased duplex thermostabilities.
摘要
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