肉豆蔻（Myristica fragrans Houtt.）和丁香（Syzygium aromaticum (L) Merr. & Perry.）50%乙醇提取物对雄性小鼠的壮阳活性：一项比较研究。
Aphrodisiac activity of 50% ethanolic extracts of Myristica fragrans Houtt. (nutmeg) and Syzygium aromaticum (L) Merr. & Perry. (clove) in male mice: a comparative study.
作者信息
Ahmad Shamshad, Latif Abdul, Qasmi Iqbal Ahmad
机构信息
Department of Ilmul Advia (Unani Pharmacology), Faculty of Unani Medicine, Aligarh Muslim University, Aligarh-202002, India.
出版信息
BMC Complement Altern Med. 2003 Oct 20;3:6. doi: 10.1186/1472-6882-3-6.
BACKGROUND
Spices are considered as sexual invigorators in the Unani System of Medicine. In order to explore the sexual function improving effect of Myristica fragrans Houtt. (nutmeg) and Syzygium aromaticum (L) Merr. & Perry. (clove) an experimental study was conducted in normal male mice.
METHODS
The extracts (50% ethanolic) of nutmeg and clove were administered (500 mg/kg; p.o.) to different groups of male Swiss mice. Mounting behaviour, mating performance, and general short term toxicity of the test drugs were determined and compared with the standard drug Penegra (Sildenafil citrate).
RESULTS
The extracts of the nutmeg and clove were found to stimulate the mounting behaviour of male mice, and also to significantly increase their mating performance. The drugs were devoid of any conspicuous general short term toxicity.
CONCLUSION
The extracts (50% ethanolic) of nutmeg and clove enhanced the sexual behaviour of male mice.
背景
在尤纳尼医学体系中，香料被视为性兴奋剂。为了探究肉豆蔻和丁香对性功能的改善作用，对正常雄性小鼠进行了一项实验研究。
方法
将肉豆蔻和丁香的提取物（50%乙醇提取物）以500毫克/千克的剂量口服给予不同组别的雄性瑞士小鼠。测定受试药物的骑跨行为、交配性能和一般短期毒性，并与标准药物必利劲（枸橼酸西地那非）进行比较。
结果
发现肉豆蔻和丁香的提取物能刺激雄性小鼠的骑跨行为，还能显著提高它们的交配性能。这些药物没有任何明显的一般短期毒性。
结论
肉豆蔻和丁香的提取物（50%乙醇提取物）增强了雄性小鼠的性行为。
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