Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, International Medical University, Kuala Lumpur, Malaysia.
Yale J Biol Med. 2020 Jun 29;93(2):307-325. eCollection 2020 Jun.
Diabetes, characterized by hyperglycemia, is one of the most significant metabolic diseases, reaching alarming pandemic proportions. It can be due to the defects in insulin action, or secretion, or both. The global prevalence of diabetes is estimated at 425 million people in 2017, and expected to rise to 629 million by 2045 due to an increasing trend of unhealthy lifestyles, physical inactivity, and obesity. Several treatment options are available to diabetics, however, some of the antidiabetic drugs result in adverse side effects such as hypoglycemia. Hence, there has been a proliferation of studies on natural products with antidiabetic effects, including plants from the Myrtaceae family, such as , and more significantly, sp. Previous studies have shown that a number of species had potent antidiabetic effects and were safe for consumption. This review aims to discuss the antidiabetic potential of sp., based on and evidence.
糖尿病是以高血糖为特征的最主要的代谢疾病之一，其流行程度已达到令人震惊的地步。它可能是由于胰岛素作用或分泌缺陷，或两者兼有。全球糖尿病患病率在 2017 年估计为 4.25 亿人，预计到 2045 年将上升至 6.29 亿人，原因是不健康的生活方式、缺乏身体活动和肥胖的流行趋势不断增加。糖尿病患者有多种治疗选择，但一些抗糖尿病药物会导致低血糖等不良反应。因此，人们对具有抗糖尿病作用的天然产物进行了大量研究，包括桃金娘科植物，如、、和更重要的是、。先前的研究表明，一些种具有很强的抗糖尿病作用，并且可以安全食用。本综述旨在根据和证据讨论 sp. 的抗糖尿病潜力。
