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脊髓损伤相关慢性疼痛患者所采用治疗方法的类型及有效性:疼痛和心理社会特征的影响

Types and effectiveness of treatments used by people with chronic pain associated with spinal cord injuries: influence of pain and psychosocial characteristics.

作者信息

Widerström-Noga E G, Turk D C

机构信息

The Miami Project to Cure Paralysis, University of Miami, Miami, FL 33136, USA.

出版信息

Spinal Cord. 2003 Nov;41(11):600-9. doi: 10.1038/sj.sc.3101511.

DOI:10.1038/sj.sc.3101511
PMID:14569261
Abstract

STUDY DESIGN

Postal survey.

OBJECTIVES

Because of the high prevalence and inadequate control of pain following spinal cord injury (SCI), it is important to have information about the factors associated with the use of specific pain therapies. We conducted this study to evaluate the ability of pain characteristics and psychosocial factors to predict the use of treatments.

SETTING

The Miami Project to Cure Paralysis (Miami, FL, USA).

METHODS

People with SCI (n=120) were mailed a packet containing a questionnaire with questions regarding demographic factors, pain characteristics, and pain treatments along with a copy of the Multidimensional Pain Inventory.

RESULTS

A total of 59% of the respondents had been prescribed treatment or self-initiated efforts to treat pain over the previous 18-month period. The most common treatments used by this sample were massage (26.6%), opioids (22.5%) and nonsteroidal anti-inflammatory drugs (NSAIDs) (20%). The most effective treatments overall were 'physical therapies' with 50% receiving these treatments indicating that their pain was 'considerably reduced' or that they were 'pain free.' Opioids and anticonvulsants were perceived to be the most effective pharmacological agents prescribed (33.3 and 23.8% reporting their pain was considerably better or eliminated, respectively). People using prescription medication reported significantly greater pain severity, more widespread pain, more descriptive adjectives, more evoked pain, greater difficulty in dealing with pain, and more interference and decreased activity levels due to pain, compared to people not using prescription medication. A combination of greater difficulty in dealing with pain, intense pain, presence of evoked pain, and higher level of perceived support from significant others was predictive of taking prescription medication.

CONCLUSION

People taking prescription medication reported significantly more intense pain with neuropathic characteristics that significantly affected daily life and routine activities. A substantial percentage of individuals with pain related to SCI did not obtain significant pain relief from prescription medications. None of the factors assessed predicted the use of nonprescription treatments. The results of this study confirm the inadequacy of available modalities to manage chronic pain related to SCI.

摘要

研究设计

邮寄问卷调查。

目的

由于脊髓损伤(SCI)后疼痛的高发生率及控制不佳,了解与特定疼痛治疗方法使用相关的因素很重要。我们开展本研究以评估疼痛特征和心理社会因素预测治疗方法使用的能力。

地点

迈阿密瘫痪治疗项目(美国佛罗里达州迈阿密)。

方法

向脊髓损伤患者(n = 120)邮寄一个资料包,其中包含一份问卷,涉及人口统计学因素、疼痛特征和疼痛治疗方法,以及一份多维疼痛量表。

结果

在过去18个月期间,共有59%的受访者接受过规定治疗或自行采取措施治疗疼痛。该样本中最常用的治疗方法是按摩(26.6%)、阿片类药物(22.5%)和非甾体抗炎药(NSAIDs)(20%)。总体而言,最有效的治疗方法是“物理治疗”,50%接受这些治疗的患者表示疼痛“显著减轻”或“无痛”。阿片类药物和抗惊厥药被认为是最有效的处方药物(分别有33.3%和23.8%的患者报告疼痛显著改善或消除)。与未使用处方药的患者相比,使用处方药的患者报告疼痛严重程度更高、疼痛范围更广、描述性形容词更多、诱发痛更多、应对疼痛的困难更大,以及因疼痛导致的干扰和活动水平下降更多。应对疼痛困难更大、疼痛剧烈、存在诱发痛以及来自重要他人的感知支持水平较高这几个因素共同预测了使用处方药的情况。

结论

服用处方药的患者报告有更强烈的、具有神经病理性特征的疼痛,这对日常生活和日常活动有显著影响。相当一部分与脊髓损伤相关疼痛的患者未从处方药中获得显著的疼痛缓解。所评估的因素均未预测非处方治疗方法的使用。本研究结果证实了现有治疗方式在管理与脊髓损伤相关的慢性疼痛方面的不足。

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