角膜感觉测量法在筛查糖尿病视网膜病变中的应用价值。
Usefulness of corneal esthesiometry for screening diabetic retinopathy.
作者信息
Alvarenga Lênio Souza, Martins Elisabeth Nogueira, Grottone Gustavo Teixeira, Morales Paulo Henrique Avila, Paranhos Augusto, Freitas Denise de, Scarpi Marinho Jorge
机构信息
Departamento de Oftalmologia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
出版信息
Rev Saude Publica. 2003 Oct;37(5):609-15. doi: 10.1590/s0034-89102003000500010. Epub 2003 Oct 9.
OBJECTIVE
To assess the usefulness of corneal esthesiometry for screening diabetic retinopathy.
METHODS
A cross-sectional study was carried out comprising 575 patients attending a diabetic retinopathy-screening program in the city of São Paulo. Corneal esthesiometry was assessed with the Cochet-Bonnet esthesiometer. The presence of diabetic retinopathy was detected with indirect fundoscopy. The validity of corneal esthesiometry in identifying diabetic retinopathy was evaluated by the Receiver Operating Characteristic (ROC) curve.
RESULTS
Sensitivity and specificity analyses of the corneal esthesiometry for detecting the stages of diabetic retinopathy using different cut-offs showed values less than 80%. The best indices (72.2% sensitivity and 57.4% specificity) were obtained for the identification of patients with proliferative diabetic retinopathy.
CONCLUSIONS
In the study series, corneal esthesiometry was not a good indicator of diabetic retinopathy.
目的
评估角膜感觉测量法在筛查糖尿病视网膜病变中的作用。
方法
开展了一项横断面研究，纳入了575名在圣保罗市参加糖尿病视网膜病变筛查项目的患者。使用科谢 - 博内角膜知觉计评估角膜感觉测量法。通过间接检眼镜检查来检测糖尿病视网膜病变的存在。通过受试者操作特征（ROC）曲线评估角膜感觉测量法在识别糖尿病视网膜病变方面的有效性。
结果
使用不同临界值对角膜感觉测量法检测糖尿病视网膜病变各阶段的敏感性和特异性分析显示，其值均低于80%。在识别增殖性糖尿病视网膜病变患者时获得了最佳指标（敏感性为72.2%，特异性为57.4%）。
结论
在该研究系列中，角膜感觉测量法并非糖尿病视网膜病变的良好指标。
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