Saini J S, Khandalavla B
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Can J Ophthalmol. 1995 Apr;30(3):142-6.
To assess corneal epithelial fragility in non-insulin-dependent diabetes mellitus (NIDDM) and its association with retinopathy.
Survey.
University-affiliated hospital in Chandigarh, India.
Seventy patients with NIDDM selected at random and 35 age-matched healthy control subjects recruited from hospital staff and their relatives.
Corneal epithelial fragility, as measured with an esthesiometer.
Mean corneal epithelial fragility values were significantly higher for the diabetic subjects without retinopathy than for the control subjects (p < 0.05). The mean epithelial fragility values for the eyes with diabetic proliferative retinopathy and those with nonproliferative retinopathy were significantly higher (by 84% and 41% respectively) than the mean value for the diabetic subjects without retinopathy (p < 0.05). There was no significant difference in mean epithelial fragility values between the proliferative and nonproliferative retinopathy groups.
Eyes with diabetic retinopathy demonstrate increased corneal epithelial fragility.
评估非胰岛素依赖型糖尿病（NIDDM）患者的角膜上皮脆性及其与视网膜病变的关联。
调查。
印度昌迪加尔的大学附属医院。
随机选取的70例NIDDM患者以及从医院工作人员及其亲属中招募的35名年龄匹配的健康对照者。
用感觉测量仪测量的角膜上皮脆性。
无视网膜病变的糖尿病患者的平均角膜上皮脆性值显著高于对照组（p < 0.05）。患有糖尿病增殖性视网膜病变的眼睛和患有非增殖性视网膜病变的眼睛的平均上皮脆性值显著更高（分别高84%和41%），高于无视网膜病变的糖尿病患者的平均值（p < 0.05）。增殖性视网膜病变组和非增殖性视网膜病变组之间的平均上皮脆性值无显著差异。
患有糖尿病视网膜病变的眼睛角膜上皮脆性增加。
