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[金刚烷胺急性中毒的心脏毒性:一例报告]

[Cardiotoxicity of amantadine in acute poisoning: a case report].

作者信息

Szpak Dorota, Piotrowski Wiesław, Groszek Barbara

机构信息

Klinika Toksykologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, WSS im. L. Rydygiera 31-826 Kraków, Os. Złotej Jesieni 1.

出版信息

Przegl Lek. 2003;60(4):265-7.

Abstract

We report the case of an adolescent, 15-year-old woman, who ingested 4.0 g of amantadine in a suicide attempt 2 hours before admission. She developed central nervous system symptoms including confusion and psychomotor agitation. The main cardiovascular symptoms were due to disturbances in atrioventricular conduction and propagation of stimuli in sinus node. All cardiovascular symptoms disappearanced after 12 hours of admission, CNS symptoms were observed 48 hours. No other systems were involved. She was discharged in a good state on day 5th.

摘要

我们报告了一例15岁青春期女性的病例,该患者在入院前2小时因自杀企图摄入了4.0克金刚烷胺。她出现了包括意识模糊和精神运动性激越在内的中枢神经系统症状。主要的心血管症状是由于房室传导和窦房结刺激传导紊乱所致。入院12小时后所有心血管症状消失,中枢神经系统症状持续了48小时。未累及其他系统。她于第5天康复出院。

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