Tang Min D, Golden Andrew P, Tien Joe
Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA.
J Am Chem Soc. 2003 Oct 29;125(43):12988-9. doi: 10.1021/ja037677h.
This Communication describes the use of patterned elastomeric stamps to mold, release, and stack hydrogels into three-dimensional microstructures. Molding of gels against stamps derivatized by a hexa(ethylene glycol)-terminated self-assembled monolayer or by an adsorbed monolayer of bovine serum albumin allowed the application of several soft lithographic techniques (replica molding, microtransfer molding, and micromolding in capillaries) to the microfabrication of gels. We describe procedures to generate coplanar or bilayered composites of gels.
本通讯描述了使用图案化弹性体印章将水凝胶模塑、脱模并堆叠成三维微结构的方法。将凝胶模塑在由六（乙二醇）封端的自组装单分子层或吸附的牛血清白蛋白单分子层衍生化的印章上，使得几种软光刻技术（复制模塑、微转移模塑和毛细管微模塑）能够应用于凝胶的微加工。我们描述了生成凝胶共面或双层复合材料的程序。
