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原发性骨关节炎与职业:一项对10412例有症状患者的全国横断面调查。

Primary osteoarthritis and occupations: a national cross sectional survey of 10 412 symptomatic patients.

作者信息

Rossignol M, Leclerc A, Hilliquin P, Allaert F A, Rozenberg S, Valat J-P, Avouac B, Coste P, Savarieau B, Fautrel B

机构信息

Department of Epidemiology, Biostatistics and Occupational Health, McGill University and Montreal Department of Public Health, Montreal, Canada.

出版信息

Occup Environ Med. 2003 Nov;60(11):882-6. doi: 10.1136/oem.60.11.882.

Abstract

AIMS

To describe the age standardised prevalence of symptomatic osteoarthritis (OA) in a nationwide cross sectional survey of 10 412 patients in France, and their functional and work limitations.

METHODS

Cases in the survey were compared with their expected counterpart by age, gender, and occupational groupings using data from the 1998 French National Survey on Health Impairment and Disability.

RESULTS

Women represented 66.2% of the sample; mean age was 66.2 years. One third of patients had OA of the knee, 16% of the hip, and 12% of the hand; a third had multiple joint OA. Peak prevalence of symptomatic OA was in the 60-69 year category in women and in the 70-79 year category in men. Agricultural workers showed a significant excess prevalence of OA, with an observed to expected (O/E) ratio of 1.7 in women and 2.3 in men. Linear trends in prevalences between white collar, "mixed" collar, and blue collar workers were also significant, with odds ratios respectively of 1.0, 2.9, and 2.6 in women and 1.0, 1.2, and 1.7 in men. Specific excess prevalence was found in women among housekeepers (O/E 4.4), and in men among unskilled labour workers (O/E 10.3) and truck drivers (O/E 6.7). Total work disability was highest among blue collar workers and partial disability among agricultural workers.

CONCLUSION

Results contribute to the mounting evidence that OA is potentially aetiologically linked to occupation in a sizeable segment of the population and that OA can no longer be considered an inevitable disease of ageing.

摘要

目的

在法国对10412名患者进行的全国性横断面调查中,描述症状性骨关节炎(OA)的年龄标准化患病率及其功能和工作限制情况。

方法

利用1998年法国全国健康损害与残疾调查的数据,按照年龄、性别和职业分组,将调查中的病例与其预期情况进行比较。

结果

女性占样本的66.2%;平均年龄为66.2岁。三分之一的患者患有膝关节OA,16%患有髋关节OA,12%患有手部OA;三分之一的患者患有多关节OA。症状性OA的患病率高峰在女性的60 - 69岁年龄段和男性的70 - 79岁年龄段。农业工人的OA患病率显著过高,女性的观察到的与预期的(O/E)比率为1.7,男性为2.3。白领、“混合”领和蓝领工人之间患病率的线性趋势也很显著,女性的优势比分别为1.0、2.9和2.6,男性为1.0、1.2和1.7。在女性的家政人员中(O/E 4.4)以及男性的非技术工人中(O/E 10.3)和卡车司机中(O/E 6.7)发现了特定的过高患病率。完全工作残疾在蓝领工人中最高,部分残疾在农业工人中最高。

结论

这些结果进一步证明,在相当一部分人群中,OA可能在病因上与职业有关,而且OA不能再被视为一种不可避免的衰老疾病。

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