Meichle A, Philipp A, Eilers M
Zentrum für Molekulare Biologie (ZMBH), Im Neuenheimer Feld, Heidelberg, Germany.
Biochim Biophys Acta. 1992 Dec 16;1114(2-3):129-46. doi: 10.1016/0304-419x(92)90011-m.
The functions of Myc proteins have remained a mystery for a number of years. Recent data have now provided us with a clear working hypothesis of how myc may act. What appears to be still missing is a link between the biochemical properties of this oncoprotein and its observed biological effects. Further research will be necessary to fill this void.
多年来,Myc蛋白的功能一直是个谜。最近的数据现在为我们提供了一个关于myc可能如何发挥作用的明确工作假设。目前似乎仍然缺失的是这种癌蛋白的生化特性与其所观察到的生物学效应之间的联系。需要进一步的研究来填补这一空白。