Cutignano Adele, Fontana Angelo, Renzulli Licia, Cimino Guido
Istituto di Chimica Biomolecolare del CNR, Via Campi Flegrei 34, 80078, Pozzuoli, Napoli, Italy.
J Nat Prod. 2003 Oct;66(10):1399-401. doi: 10.1021/np0300176.
Four new alpha-pyrone-containing propionates (5-8) and an unprecedented hydroperoxide 9 have been isolated from the mantle extract of Placida dendritica, a Mediterranean sacoglossan that lives upon the green alga Bryopsis plumosa. The new metabolites co-occur with the related compounds 1-4, which have been described in previous studies of the mollusc. The presence of 9 opens intriguing perspectives on the ecological role of placidenes. This paper reports the isolation and structural elucidation of the new compounds 5-9.
从地中海裸鳃亚目动物Placida dendritica的外套膜提取物中分离出了四种新的含α-吡喃酮的丙酸酯（5-8）和一种前所未有的氢过氧化物9，Placida dendritica以绿藻羽藻为食。这些新的代谢产物与相关化合物1-4共同存在，后者已在该软体动物的先前研究中有所描述。化合物9的存在为普拉西地烯的生态作用开启了有趣的研究前景。本文报道了新化合物5-9的分离和结构解析。
