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1
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities.利用具有特定设计DNA序列特异性的试剂对内源基因功能进行治疗性调控。
Nucleic Acids Res. 2003 Nov 1;31(21):6064-78. doi: 10.1093/nar/gkg815.
2
Regulation of gene expression by small molecules.小分子对基因表达的调控
Nature. 1997 May 8;387(6629):202-5. doi: 10.1038/387202a0.
3
Specificity landscapes of DNA binding molecules elucidate biological function.DNA 结合分子的特异性景观阐明了生物学功能。
Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4544-9. doi: 10.1073/pnas.0914023107. Epub 2010 Feb 22.
4
Combinatorial determination of sequence specificity for nanomolar DNA-binding hairpin polyamides.用于纳摩尔级DNA结合发夹型聚酰胺的序列特异性的组合测定。
Biochemistry. 2003 Jun 10;42(22):6891-903. doi: 10.1021/bi027373s.
5
Regulation of gene expression with pyrrole-imidazole polyamides.利用吡咯-咪唑聚酰胺调控基因表达
J Biotechnol. 2004 Aug 26;112(1-2):195-220. doi: 10.1016/j.jbiotec.2004.03.018.
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Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex.转录因子IIIA-DNA复合物中小沟结合锌指的重要性。
J Mol Biol. 1997 Dec 12;274(4):439-45. doi: 10.1006/jmbi.1997.1411.
7
[Advances in the chemical and biological studies of polyamides].[聚酰胺的化学与生物学研究进展]
Yao Xue Xue Bao. 2008 Nov;43(11):1089-93.
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Programmable DNA binding oligomers for control of transcription.用于转录调控的可编程DNA结合寡聚物
Curr Med Chem Anticancer Agents. 2005 Jul;5(4):373-87. doi: 10.2174/1568011054222346.
9
[Artificial transcription factors as tools for gene expression manipulation].[人工转录因子作为基因表达调控工具]
Sheng Wu Gong Cheng Xue Bao. 2005 May;21(3):341-7.
引用本文的文献
1
H-ACO with Consecutive Bases Pairing Constraint for Designing DNA Sequences.用于设计DNA序列的具有连续碱基配对约束的H-ACO
Interdiscip Sci. 2024 Sep;16(3):593-607. doi: 10.1007/s12539-024-00614-1. Epub 2024 Apr 29.
2
How acidic amino acid residues facilitate DNA target site selection.酸性氨基酸残基如何促进 DNA 靶位点选择。
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2212501120. doi: 10.1073/pnas.2212501120. Epub 2023 Jan 12.
3
DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies.具有两性离子和带负电荷磷酸修饰的DNA：DNA三链体、双链体的形成及细胞摄取研究
Beilstein J Org Chem. 2021 Mar 29;17:749-761. doi: 10.3762/bjoc.17.65. eCollection 2021.
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RNA Biology Provides New Therapeutic Targets for Human Disease.RNA生物学为人类疾病提供了新的治疗靶点。
Front Genet. 2019 Mar 8;10:205. doi: 10.3389/fgene.2019.00205. eCollection 2019.
5
The past and presence of gene targeting: from chemicals and DNA via proteins to RNA.基因靶向的过去和现在：从化学物质和 DNA 到蛋白质再到 RNA。
Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748). doi: 10.1098/rstb.2017.0077.
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Sliding on DNA: From Peptides to Small Molecules.滑动在 DNA 上：从肽到小分子。
Angew Chem Int Ed Engl. 2016 Nov 21;55(48):15110-15114. doi: 10.1002/anie.201606768. Epub 2016 Nov 4.
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Statistical analysis of structural determinants for protein-DNA-binding specificity.蛋白质 - DNA 结合特异性结构决定因素的统计分析。
Proteins. 2016 Aug;84(8):1147-61. doi: 10.1002/prot.25061. Epub 2016 Jun 15.
8
Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer.利用乳腺癌表观遗传突变可逆性的当前及未来方法。
Breast Cancer Res. 2014 Jul 29;16(4):412. doi: 10.1186/s13058-014-0412-z.
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Optimizing scoring function of protein-nucleic acid interactions with both affinity and specificity.优化具有亲和力和特异性的蛋白质-核酸相互作用的评分函数。
PLoS One. 2013 Sep 30;8(9):e74443. doi: 10.1371/journal.pone.0074443. eCollection 2013.
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Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.人工转录因子对宫颈癌候选抑癌基因 C13ORF18 的功能验证。
Mol Oncol. 2013 Jun;7(3):669-79. doi: 10.1016/j.molonc.2013.02.017. Epub 2013 Mar 5.
本文引用的文献
1
Recognition of the DNA minor groove by pyrrole-imidazole polyamides.吡咯-咪唑聚酰胺对DNA小沟的识别
Curr Opin Struct Biol. 2003 Jun;13(3):284-99. doi: 10.1016/s0959-440x(03)00081-2.
2
Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair.用于DNA识别的替代性杂环：苯并咪唑/咪唑对。
Chemistry. 2003 May 9;9(9):2110-22. doi: 10.1002/chem.200204689.
3
Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition.用于识别DNA小沟的咪唑并吡啶/吡咯和羟基苯并咪唑/吡咯对。
J Am Chem Soc. 2003 May 14;125(19):5707-16. doi: 10.1021/ja0300158.
4
Enhancing gene targeting with designed zinc finger nucleases.利用设计的锌指核酸酶增强基因靶向作用。
Science. 2003 May 2;300(5620):764. doi: 10.1126/science.1079512.
5
Chimeric nucleases stimulate gene targeting in human cells.嵌合核酸酶可刺激人类细胞中的基因靶向作用。
Science. 2003 May 2;300(5620):763. doi: 10.1126/science.1078395.
6
Triplex-forming oligodeoxynucleotides targeting survivin inhibit proliferation and induce apoptosis of human lung carcinoma cells.靶向生存素的三链形成寡脱氧核苷酸抑制人肺癌细胞的增殖并诱导其凋亡。
Cancer Gene Ther. 2003 May;10(5):403-10. doi: 10.1038/sj.cgt.7700581.
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A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity.一种双烷基化三链形成寡核苷酸可抑制细胞内报告基因表达，并防止由于解旋酶活性导致的三链解旋。
Biochemistry. 2003 May 6;42(17):5013-24. doi: 10.1021/bi0273112.
8
Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells.控制荧光聚酰胺类似物在培养细胞中的细胞内定位。
Bioorg Med Chem Lett. 2003 May 5;13(9):1565-70. doi: 10.1016/s0960-894x(03)00152-5.
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Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog.含反应性核苷类似物的三链螺旋形成寡核苷酸介导的位点特异性诱变
Nucleic Acids Res. 2003 Mar 15;31(6):e31. doi: 10.1093/nar/gng031.
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Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.通过合成锌指转录因子对印记基因进行靶向调控。
Gene Ther. 2003 Mar;10(6):513-22. doi: 10.1038/sj.gt.3301930.
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