Blair D F, Dutcher S K
Department of Biology, University of Utah, Salt Lake City 84112.
Curr Opin Genet Dev. 1992 Oct;2(5):756-67. doi: 10.1016/s0959-437x(05)80136-4.
During the past year, significant advances have been made in the understanding of both prokaryotic and eukaryotic flagella. About 50 genes are dedicated to the assembly and operation of bacterial flagella. Recent discoveries have advanced our understanding of how these genes are regulated and how their products assemble into a functional, rotating organelle. The dynein arms of eukaryotic flagella are now also better understood. Several genes that are found in the mechanochemical macroassemblies have been cloned, and other loci have been identified, suggesting that there is even greater complexity than first expected.
在过去的一年里，我们对原核生物和真核生物鞭毛的认识取得了重大进展。大约有50个基因专门负责细菌鞭毛的组装和运作。最近的发现加深了我们对这些基因如何调控以及它们的产物如何组装成一个功能性旋转细胞器的理解。现在，我们对真核生物鞭毛的动力蛋白臂也有了更好的了解。在机械化学大分子组件中发现的几个基因已被克隆，其他位点也已被确定，这表明其复杂性比最初预期的还要高。
