Minami Masato, Kita Masakazu, Nakaya Takaaki, Yamamoto Toshiro, Kuriyama Hiroko, Imanishi Jiro
Department of Microbiology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto 602-8566, Japan.
Microbiol Immunol. 2003;47(9):681-4. doi: 10.1111/j.1348-0421.2003.tb03431.x.
The antiviral effect of 12 essential oils on herpes simplex virus type-1 (HSV-1) replication was examined in vitro. The replication ability of HSV-1 was suppressed by incubation of HSV-1 with 1% essential oils at 4 C for 24 hr. Especially, lemongrass completely inhibited the viral replication even at a concentration of 0.1%, and its antiviral activity was dependent on the concentrations of the essential oil. When Vero cells were treated with the essential oil before or after viral adsorption, no antiviral activity was found, which suggests that the antiviral activity of essential oils including lemongrass may be due to the direct interaction with virions.
在体外检测了12种精油对单纯疱疹病毒1型（HSV-1）复制的抗病毒作用。将HSV-1与1%的精油在4℃孵育24小时，可抑制HSV-1的复制能力。特别是，柠檬草即使在浓度为0.1%时也能完全抑制病毒复制，其抗病毒活性取决于精油的浓度。当在病毒吸附之前或之后用精油处理Vero细胞时，未发现抗病毒活性，这表明包括柠檬草在内的精油的抗病毒活性可能是由于与病毒粒子的直接相互作用。
