Sako Yasushi, Yanagida Toshio
Nanobiology Laboratories, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.
Nat Rev Mol Cell Biol. 2003 Sep;Suppl:SS1-5.
Recent progress in single-molecule detection techniques has allowed us to visualize the dynamic behaviour and reaction kinetics of individual biological molecules inside living cells. Single-molecule visualization provides a direct way to quantify, with a high spatial and temporal resolution, biological events inside cells at the single-molecule level. In this article, we discuss how single-molecule visualization can be used in cell biology.
单分子检测技术的最新进展使我们能够可视化活细胞内单个生物分子的动态行为和反应动力学。单分子可视化提供了一种直接的方法,能够在单分子水平上以高空间和时间分辨率对细胞内的生物事件进行量化。在本文中,我们将讨论单分子可视化如何应用于细胞生物学。