Lewis Aaron, Taha Hesham, Strinkovski Alina, Manevitch Alexandra, Khatchatouriants Artium, Dekhter Rima, Ammann Erich
Division of Applied Physics, The Hebrew University of Jerusalem, Jerusalem 93707 Israel.
Nat Biotechnol. 2003 Nov;21(11):1378-86. doi: 10.1038/nbt898.
Near-field optics uniquely addresses problems of x, y and z resolution by spatially confining the effect of a light source to nanometric domains. The problems in using far-field optics (conventional optical imaging through a lens) to achieve nanometric spatial resolution are formidable. Near-field optics serves a bridging role in biology between optical imaging and scanned probe microscopy. The integration of near-field and scanned probe imaging with far-field optics thus holds promise for solving the so-called inverse problem of optical imaging.
近场光学通过将光源的作用在空间上限制于纳米尺度区域,独特地解决了x、y和z分辨率的问题。使用远场光学(通过透镜进行传统光学成像)来实现纳米级空间分辨率面临着巨大的问题。近场光学在生物学中起到了光学成像与扫描探针显微镜之间的桥梁作用。因此,将近场和扫描探针成像与远场光学相结合有望解决所谓的光学成像逆问题。