Robson Matthew D, Gatehouse Peter D, Bydder Mark, Bydder Graeme M
Oxford University Center for Clinical Magnetic Resonance Research, MRS Unit, John Radcliffe Hospital.
J Comput Assist Tomogr. 2003 Nov-Dec;27(6):825-46. doi: 10.1097/00004728-200311000-00001.
The background underpinning the clinical use of ultrashort echo-time (UTE) pulse sequences for imaging tissues or tissue components with short T2s is reviewed. Tissues properties are discussed, and tissues are divided into those with a majority of short T2 relaxation components and those with a minority. Features of the basic physics relevant to UTE imaging are described including the fact that when the radiofrequency pulse duration is of the order T2, rotation of tissue magnetization into the transverse plane is incomplete. Consequences of the broad line-width of short T2 components are also discussed including their partial saturation by off-resonance fat suppression pulses as well as multislice and multiecho imaging. The need for rapid data acquisition of the order T2 is explained. The basic UTE pulse sequence with its half excitation pulse and radial imaging from the center of k-space is described together with options that suppress fat and/or long T2 components. Image interpretation is discussed. Clinical features of the imaging of cortical bone, tendons, ligaments, menisci, and periosteum as well as brain, liver, and spine are illustrated. Short T2 components in all of these tissues may show high signals. Possible future developments are outlined as are technical limitations.
本文回顾了超短回波时间(UTE)脉冲序列在临床用于对具有短T2值的组织或组织成分进行成像的背景知识。讨论了组织特性,并将组织分为以短T2弛豫成分为主的组织和以短T2弛豫成分为少数的组织。描述了与UTE成像相关的基本物理特征,包括当射频脉冲持续时间约为T2时,组织磁化矢量向横向平面的旋转不完全。还讨论了短T2成分宽线宽的后果,包括它们被偏离共振脂肪抑制脉冲部分饱和以及多层和多回波成像。解释了对约为T2量级的快速数据采集的需求。描述了具有半激发脉冲和从k空间中心进行径向成像的基本UTE脉冲序列,以及抑制脂肪和/或长T2成分的选项。讨论了图像解读。展示了皮质骨、肌腱、韧带、半月板、骨膜以及脑、肝和脊柱成像的临床特征。所有这些组织中的短T2成分可能显示高信号。概述了未来可能的发展以及技术局限性。