Nir-Paz Ran, Elinav Hila, Pierard Gerald E, Walker David, Maly Alexander, Shapiro Mervyn, Barton Richard C, Polacheck Itzhack
Department of Clinical Microbiology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
J Clin Microbiol. 2003 Nov;41(11):5298-301. doi: 10.1128/JCM.41.11.5298-5301.2003.
Dermatophytes are common pathogens of skin but rarely cause invasive disease. We present a case of deep infection by Trichophyton rubrum in an immunocompromised patient. T. rubrum was identified by morphological characteristics and confirmed by PCR. Invasiveness was apparent by histopathology and immunohistochemistry. The patient was treated successfully with itraconazole.
皮肤癣菌是常见的皮肤病原体,但很少引起侵袭性疾病。我们报告一例免疫功能低下患者发生红色毛癣菌深部感染的病例。通过形态学特征鉴定出红色毛癣菌,并经聚合酶链反应(PCR)确认。组织病理学和免疫组织化学显示有侵袭性。该患者接受伊曲康唑治疗成功。