Nettis E, Marcandrea M, Colanardi M C, Paradiso M T, Ferrannini A, Tursi A
Department of Medical Clinic, Immunology and Infectious Diseases, Section of Allergy and Clinical Immunology, University of Bari, Bari, Italy.
Allergy. 2003 Dec;58(12):1304-7. doi: 10.1046/j.1398-9995.2003.00346.x.
In the workplace, the skin is at high risk of exposure to chemicals and other contaminants, and occupational dermatitis is an important field of study.
We evaluated 230 patients referred to our clinic because they were affected by dermatitis suspected to be of occupational and allergic origin. They were tested with the allergens of the GIRDCA standard series, and with supplementary series when indicated.
Among the 230 subjects, 49 were positive only to supplementary series (26.3% of all allergic contact dermatitis), while 130 (69.9% of all allergic contact dermatitis) were considered to have an occupational allergic contact dermatitis diagnosed by the standard series alone. The most frequent occupations of the patients were health care workers and hairdressers/beauticians. The most common agents responsible for occupational allergic contact dermatitis were metals and para-phenylenediamine.
As the standard series detected a relatively low proportion of occupational allergic contact dermatitis, it is not adequate to recognize an occupational allergic contact dermatitis, certain supplementary series should also to be tested. However, even if such occupational series are used, we remain likely to continue to underestimate the frequency of occupational allergic contact dermatitis, because workers come into contact with a large number of substances that are often unknown.
在工作场所，皮肤极易接触化学品和其他污染物，职业性皮炎是一个重要的研究领域。
我们评估了230名因疑似职业性和过敏性皮炎而转诊至我们诊所的患者。他们接受了GIRDCA标准系列过敏原检测，并在必要时接受补充系列检测。
在这230名受试者中，49人仅对补充系列呈阳性（占所有过敏性接触性皮炎的26.3%），而130人（占所有过敏性接触性皮炎的69.9%）仅通过标准系列就被诊断为职业性过敏性接触性皮炎。患者最常见的职业是医护人员和美发师/美容师。导致职业性过敏性接触性皮炎最常见的因素是金属和对苯二胺。
由于标准系列检测出的职业性过敏性接触性皮炎比例相对较低，仅靠它不足以识别职业性过敏性接触性皮炎，还应检测某些补充系列。然而，即使使用了这样的职业系列，我们仍可能继续低估职业性过敏性接触性皮炎的发生率，因为工人会接触大量通常未知的物质。
