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[HELLP综合征——一种危及生命的妊娠并发症]

[HELLP syndrome--a life-threatening pregnancy complication].

作者信息

Aune B, Oian P

机构信息

Kvinneklinikken Regionsykehuset i Tromsø.

出版信息

Tidsskr Nor Laegeforen. 1992 Oct 20;112(25):3184-6.

PMID:1462289
Abstract

A serious complication to pregnancy-induced hypertension and preeclampsia is the HELLP syndrome (H - haemolysis, EL - elevated liver enzymes, LP - low platelet count). Perinatal and maternal mortality are reported to be high, 7-60% and 2-24%, respectively. A non-obstetric diagnosis is often made, such as gastrointestinal or haematologic disease. Typical symptoms are epigastric and right upper-quadrant pain and tenderness, nausea and vomiting. Recognition of the clinical and laboratory findings is important, so that early, aggressive therapy can be initiated in order to prevent maternal and perinatal death. We present data from 14 patients with the HELLP syndrome treated in our hospital. There was one intrauterine death. The other infants were discharged in good condition. Two of the patients had eclampsia.

摘要

妊娠高血压和先兆子痫的一种严重并发症是HELLP综合征(H - 溶血,EL - 肝酶升高,LP - 血小板计数降低)。据报道,围产期和孕产妇死亡率很高,分别为7% - 60%和2% - 24%。常作出非产科诊断,如胃肠道或血液系统疾病。典型症状为上腹部和右上腹疼痛及压痛、恶心和呕吐。认识临床和实验室检查结果很重要,以便能够启动早期积极治疗,预防孕产妇和围产期死亡。我们展示了我院治疗的14例HELLP综合征患者的数据。有1例宫内死亡。其他婴儿出院时情况良好。2例患者发生子痫。

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