Tybjerg J, Gulmann N C
Gerontopsykiatrisk afdeling D, Psykiatrisk Hospital i Arhus.
Ugeskr Laeger. 1992 Nov 2;154(45):3126-9.
In 32 nursing homes selected at random in the 16 counties in Denmark, the use of psychotropic medication was studied in all residents aged over 65 years (1454 persons) by interview of nursing staff and review of treatment records regarding drug group, dose, duration of treatment and target symptoms. Psychotropic prescriptions were recorded in 56% of the elderly. The frequency of residents receiving daily treatment with neuroleptics was 20% and for anxiolytics, hypnotics and antidepressants 13%, 33% and 11%, respectively. The duration of treatment was two to three years. The indications were mostly unspecified behavioural disturbances. The use reflects the high psychiatric morbidity in nursing home residents, especially regarding dementia. From what is known of therapeutic efficacy and side-effects, it is concluded that the prescription rate is too high, duration of treatment much longer than necessary and that drugs inappropriate for elderly are often used.
在丹麦16个县随机挑选的32家养老院中,通过与护理人员面谈并查阅治疗记录,研究了所有65岁以上居民(1454人)使用精神药物的情况,记录内容包括药物类别、剂量、治疗时长和目标症状。56%的老年人有精神类药物处方记录。接受每日抗精神病药物治疗的居民比例为20%,接受抗焦虑药、催眠药和抗抑郁药治疗的居民比例分别为13%、33%和11%。治疗时长为两到三年。用药指征大多是未明确说明的行为障碍。这种用药情况反映出养老院居民中精神疾病发病率很高,尤其是痴呆症患者。从已知的治疗效果和副作用来看,得出的结论是处方率过高,治疗时长远超必要时长,而且经常使用对老年人不合适的药物。