吸烟与衰老对人脱落颊黏膜细胞微核频率的影响。
Effect of smoking and aging on micronucleus frequencies in human exfoliated buccal cells.
作者信息
Konopacka M
机构信息
Department of Experimental and Clinical Radiobiology; Institute of Oncology, 44-100 Gliwice, Poland.
出版信息
Neoplasma. 2003;50(5):380-2.
In the present work the frequency of micronuclei (MN) in exfoliated buccal cells in 120 healthy individuals with relation to sex, age and smoking was investigated. Neither age nor sex showed any effect on the level of micronuclei. Smoking has shown a significant effect upon basal DNA damage. In the present study the calculated background frequency of micronuclei (per mille) in oral epithelial cells of 50 smokers and 70 non-smokers were 1.50 (+/-0.47) and 0.55 (+/-0.32), respectively.
在本研究中，对120名健康个体颊部脱落细胞中的微核（MN）频率与性别、年龄和吸烟的关系进行了调查。年龄和性别对微核水平均无影响。吸烟已显示出对基础DNA损伤有显著影响。在本研究中，50名吸烟者和70名非吸烟者口腔上皮细胞中微核的计算背景频率（千分率）分别为1.50（±0.47）和0.55（±0.32）。
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