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肉桂可改善2型糖尿病患者的血糖和血脂。

Cinnamon improves glucose and lipids of people with type 2 diabetes.

作者信息

Khan Alam, Safdar Mahpara, Ali Khan Mohammad Muzaffar, Khattak Khan Nawaz, Anderson Richard A

机构信息

Department of Human Nutrition, NWFP Agricultural University, Peshawar, Pakistan.

出版信息

Diabetes Care. 2003 Dec;26(12):3215-8. doi: 10.2337/diacare.26.12.3215.

Abstract

OBJECTIVE

The objective of this study was to determine whether cinnamon improves blood glucose, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol levels in people with type 2 diabetes.

RESEARCH DESIGN AND METHODS

A total of 60 people with type 2 diabetes, 30 men and 30 women aged 52.2 +/- 6.32 years, were divided randomly into six groups. Groups 1, 2, and 3 consumed 1, 3, or 6 g of cinnamon daily, respectively, and groups 4, 5, and 6 were given placebo capsules corresponding to the number of capsules consumed for the three levels of cinnamon. The cinnamon was consumed for 40 days followed by a 20-day washout period.

RESULTS

After 40 days, all three levels of cinnamon reduced the mean fasting serum glucose (18-29%), triglyceride (23-30%), LDL cholesterol (7-27%), and total cholesterol (12-26%) levels; no significant changes were noted in the placebo groups. Changes in HDL cholesterol were not significant.

CONCLUSIONS

The results of this study demonstrate that intake of 1, 3, or 6 g of cinnamon per day reduces serum glucose, triglyceride, LDL cholesterol, and total cholesterol in people with type 2 diabetes and suggest that the inclusion of cinnamon in the diet of people with type 2 diabetes will reduce risk factors associated with diabetes and cardiovascular diseases.

摘要

目的

本研究的目的是确定肉桂是否能改善2型糖尿病患者的血糖、甘油三酯、总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平。

研究设计与方法

共有60名2型糖尿病患者,30名男性和30名女性,年龄为52.2±6.32岁,被随机分为六组。第1、2和3组分别每天食用1、3或6克肉桂,第4、5和6组服用与三个肉桂剂量组所服胶囊数量对应的安慰剂胶囊。食用肉桂40天,随后有20天的洗脱期。

结果

40天后,所有三个肉桂剂量组均降低了空腹血清葡萄糖均值(18 - 29%)、甘油三酯(23 - 30%)、低密度脂蛋白胆固醇(7 - 27%)和总胆固醇(12 - 26%)水平;安慰剂组未观察到显著变化。高密度脂蛋白胆固醇的变化不显著。

结论

本研究结果表明,每天摄入1、3或6克肉桂可降低2型糖尿病患者的血清葡萄糖、甘油三酯、低密度脂蛋白胆固醇和总胆固醇水平,并提示在2型糖尿病患者饮食中加入肉桂将降低与糖尿病和心血管疾病相关的危险因素。

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