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不同室内环境中挥发性有机化合物暴露的风险评估

Risk assessment of exposure to volatile organic compounds in different indoor environments.

作者信息

Guo H, Lee S C, Chan L Y, Li W M

机构信息

Department of Civil and Structural Engineering, Research Centre for Urban Environmental Technology and Management, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

出版信息

Environ Res. 2004 Jan;94(1):57-66. doi: 10.1016/s0013-9351(03)00035-5.

Abstract

The lifetime cancer risks of exposure of cooks and food service workers, office workers, housewives, and schoolchildren in Hong Kong to volatile organic compounds (VOCs) in their respective indoor premises during normal indoor activities were assessed. The estimated cancer risk for housewives was the highest, and the second-highest lifetime cancer risk to VOC exposure was for the groups of food service and office workers. Within a certain group of the population, the lifetime cancer risk of the home living room was one to two orders of magnitude higher than that in other indoor environments. The estimated lifetime risks of food service workers were about two times that of office workers. Furthermore, the cancer risks of working in kitchen environments were approximately two times higher than the risks arising from studying in air-conditioned classrooms. The bus riders had higher average lifetime cancer risks than those travelling by Mass Transit Railway. For all target groups of people, the findings of this study show that the exposures to VOCs may lead to lifetime risks higher than 1 x 10(-6). Seven indoor environments were selected for the measurement of human exposure and the estimation of the corresponding lifetime cancer risks. The lifetime risks with 8-h average daily exposures to individual VOCs in individual environments were compared. People in a smoking home had the highest cancer risk, while students in an air-conditioned classroom had the lowest risk of cancer. Benzene accounted for about or more than 40% of the lifetime cancer risks for each category of indoor environment. Nonsmoking and smoking residences in Hong Kong had cancer risks associated with 8-h exposures of benzene above 1.8 x 10(-5) and 8.0 x 10(-5), respectively. The cancer risks associated with 1,1-dichloroethene, chloroform, methylene chloride, trichloroethene, and tetrachloroethene became more significant at selected homes and restaurants. Higher lifetime cancer risks due to exposure to styrene were only observed in the administrative and printing offices and air-conditioned classrooms. Higher lifetime cancer risks related to chloroform exposures were observed at the restaurant and the canteen.

摘要

评估了香港厨师、食品服务人员、办公室职员、家庭主妇和学童在正常室内活动期间,于各自室内场所接触挥发性有机化合物(VOCs)的终生癌症风险。家庭主妇的估计癌症风险最高,食品服务人员和办公室职员群体接触VOCs的终生癌症风险次之。在特定人群组中,家庭客厅的终生癌症风险比其他室内环境高1至2个数量级。食品服务人员的估计终生风险约为办公室职员的两倍。此外,在厨房环境中工作的癌症风险比在有空调的教室学习产生的风险高出约两倍。乘坐巴士的人平均终生癌症风险高于乘坐地铁的人。对于所有目标人群,本研究结果表明,接触VOCs可能导致终生风险高于1×10⁻⁶。选择了七个室内环境来测量人体接触情况并估计相应的终生癌症风险。比较了在各个环境中8小时平均每日接触单个VOCs的终生风险。在有吸烟的家庭中,人们的癌症风险最高,而在有空调的教室中的学生癌症风险最低。在每类室内环境中,苯占终生癌症风险的约40%或更多。香港非吸烟和吸烟住宅中,8小时接触苯的癌症风险分别高于1.8×10⁻⁵和8.0×10⁻⁵。在选定的家庭和餐馆中,与1,1 - 二氯乙烯、氯仿、二氯甲烷、三氯乙烯和四氯乙烯相关的癌症风险变得更加显著。仅在行政和印刷办公室以及有空调的教室中观察到因接触苯乙烯而导致的较高终生癌症风险。在餐馆和食堂观察到与氯仿接触相关的较高终生癌症风险。

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