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小儿胆脂瘤手术复发的预后因素

Prognostic factors of recidivism in pediatric cholesteatoma surgery.

作者信息

Ahn Soon-Hyun, Oh Seung Ha, Chang Sun O, Kim Chong-Sun

机构信息

Departments of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea.

出版信息

Int J Pediatr Otorhinolaryngol. 2003 Dec;67(12):1325-30. doi: 10.1016/j.ijporl.2003.08.002.

DOI:10.1016/j.ijporl.2003.08.002
PMID:14643476
Abstract

OBJECTIVE

To analyze the results on a series of pediatric cholesteatomas, using various preoperative factors, including some of the proposed classification systems, to identify those factors that influence the postoperative result.

METHOD

Retrospective review of 118 children with acquired cholesteatoma who underwent surgery from January 1978 to October 1999. The median observation period was 5 years, range 1-20 years. The rate of recidivism calculated using the Kaplan-Meier method and relative risk by the Cox regression model.

RESULTS

Cholesteatoma in patients less than 8 years old with mastoid involvement had significantly higher risk of recidivism than the other groups examined.

CONCLUSIONS

In this study, cholesteatoma recurred up to 5 years after operation, and long-term close follow-up is important especially in cases involving higher risk such as younger child with mastoid extension of cholesteatoma.

摘要

目的

分析一系列儿童胆脂瘤的手术结果,利用各种术前因素,包括一些提议的分类系统,以确定那些影响术后结果的因素。

方法

回顾性分析1978年1月至1999年10月间接受手术的118例获得性胆脂瘤患儿。中位观察期为5年,范围为1至20年。采用Kaplan-Meier法计算复发率,用Cox回归模型计算相对风险。

结果

8岁以下伴有乳突受累的胆脂瘤患儿复发风险显著高于其他所研究的组。

结论

在本研究中,胆脂瘤术后复发可达5年,长期密切随访很重要,尤其是在诸如胆脂瘤乳突扩展的幼儿等高危病例中。

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