Dornelles Cristina, Costa Sady S da, Meurer Luíse, Schweiger Cláudia
Pediatrics, UFRGS.
Braz J Otorhinolaryngol. 2005 Jul-Aug;71(4):536-45. doi: 10.1016/s1808-8694(15)31212-x. Epub 2005 Dec 15.
Authors debate about cholesteatomas, from the first time this word was employed, by Muller, in 1838, until the recent updates. They dissert about its definition, etiology and pathology and present basic concepts about its biology. They also make a wide review about pediatric cholesteatoma, its epidemiology and biology, and compare it with adult cholesteatoma. Finally, they describe some articles about ossicle chain erosion and its correlation with cholesteatoma perimatrix, collagen and collagenase.
从1838年穆勒首次使用“胆脂瘤”这个词至今，作者们一直在对胆脂瘤展开讨论。他们论述了胆脂瘤的定义、病因和病理，并介绍了其生物学的基本概念。他们还对小儿胆脂瘤及其流行病学和生物学进行了广泛综述，并将其与成人胆脂瘤进行了比较。最后，他们描述了一些关于听小骨链侵蚀及其与胆脂瘤基质、胶原蛋白和胶原酶相关性的文章。
