通过磁共振成像测量人类小脑的分形维数。
Fractal dimension in human cerebellum measured by magnetic resonance imaging.
作者信息
Liu Jing Z, Zhang Lu D, Yue Guang H
机构信息
Department of Biomedical Engineering, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
出版信息
Biophys J. 2003 Dec;85(6):4041-6. doi: 10.1016/S0006-3495(03)74817-6.
Abstract
Fractal dimension has been used to quantify the structures of a wide range of objects in biology and medicine. We measured fractal dimension of human cerebellum (CB) in magnetic resonance images of 24 healthy young subjects (12 men and 12 women). CB images were resampled to a series of image sets with different 3D resolutions. At each resolution, the skeleton of the CB white matter was obtained and the number of pixels belonging to the skeleton was determined. Fractal dimension of the CB skeleton was calculated using the box-counting method. The results indicated that the CB skeleton is a highly fractal structure, with a fractal dimension of 2.57 +/- 0.01. No significant difference in the CB fractal dimension was observed between men and women.
摘要
分形维数已被用于量化生物学和医学中广泛对象的结构。我们在24名健康年轻受试者（12名男性和12名女性）的磁共振图像中测量了人类小脑（CB）的分形维数。将CB图像重采样为一系列具有不同三维分辨率的图像集。在每个分辨率下，获取CB白质的骨架并确定属于该骨架的像素数量。使用盒计数法计算CB骨架的分形维数。结果表明，CB骨架是一种高度分形的结构，分形维数为2.57±0.01。男性和女性之间在CB分形维数上未观察到显著差异。
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