三叶五加叶中的羽扇豆烷型三萜羧酸

Lupane-triterpene carboxylic acids from the leaves of Acanthopanax trifoliatus.

作者信息

Kiem Phan Van, Cai Xing Fu, Minh Chau Van, Lee Jung Joon, Kim Young Ho

机构信息

Institute of Natural Products Chemistry, NCST, Caugiay, Hanoi, Vietnam.

出版信息

Chem Pharm Bull (Tokyo). 2003 Dec;51(12):1432-5. doi: 10.1248/cpb.51.1432.

DOI:10.1248/cpb.51.1432

PMID:14646325

Abstract

Two new lupane-triterpene carboxylic acids, called acantrifoic acid A (1) and acantrifoside C (2) have been isolated from the leaves of Acanthopanax trifoliatus. Based on extensive 1D and 2D NMR spectroscopic data, their chemical structures were determined as 3 alpha-acetoxy-30-hydroxylup-20(29)-ene-23,28-dioic acid and 3 alpha-acetoxy-30-hydroxylup-20(29)-ene-23,28-dioic acid 28-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester.

摘要

从三叶五加的叶子中分离出了两种新的羽扇豆烷型三萜羧酸，分别称为刺五加酸A（1）和刺五加苷C（2）。基于广泛的一维和二维核磁共振光谱数据，确定它们的化学结构分别为3α-乙酰氧基-30-羟基羽扇-20（29）-烯-23,28-二酸和3α-乙酰氧基-30-羟基羽扇-20（29）-烯-23,28-二酸28-O-α-L-鼠李糖基-（1→4）-β-D-葡萄糖基-（1→6）-β-D-葡萄糖基酯。