Weber Oliver M, Martin Alastair J, Higgins Charles B
Department of Radiology, University of California-San Francisco, San Francisco, California 94143, USA.
Magn Reson Med. 2003 Dec;50(6):1223-8. doi: 10.1002/mrm.10653.
Current implementations of coronary artery magnetic resonance angiography (MRA) suffer from limited coverage of the coronary arterial system. Whole-heart coronary MRA was implemented based on a free-breathing steady-state free-precession (SSFP) technique with magnetization preparation. The technique was compared to a similar implementation of conventional, thin-slab coronary MRA in 12 normal volunteers. Three thin-slab volumes were prescribed: 1) a transverse slab, covering the left main (LM) artery and proximal segments of the left anterior ascending (LAD) and left circumflex (LCX) coronary arteries; 2) a double-oblique slab covering the right coronary artery (RCA); and 3) a double-oblique slab covering the proximal and distal segments of the LCX. The whole-heart data set was reformatted in identical orientations. Visible vessel length, vessel sharpness, and vessel diameter were determined and compared separately for each vessel. Whole-heart coronary MRA visualized LM/LAD (11.7 +/- 3.4 cm) and LCX (6.9 +/- 3.6 cm) over a significantly longer distance than the transverse volume (LM/LAD, 6.1 +/- 1.1 cm, P < 0.001; LCX, 4.2 +/- 1.2 cm, P < 0.05). Improvements in visible vessel length for RCA and LCX in the whole-heart approach vs. their respective targeted volumes were not significant. It is concluded that the whole-heart coronary MRA technique improves visible vessel length and facilitates high-quality coronary MRA of the complete coronary artery tree in a single measurement.
目前冠状动脉磁共振血管造影（MRA）的实施存在冠状动脉系统覆盖范围有限的问题。基于自由呼吸稳态自由进动（SSFP）技术并结合磁化准备实现了全心冠状动脉MRA。该技术与12名正常志愿者中类似的传统薄层冠状动脉MRA实施方法进行了比较。规定了三个薄层容积：1）一个横向薄层，覆盖左主干（LM）动脉以及左前降支（LAD）和左旋支（LCX）冠状动脉的近端节段；2）一个双斜薄层，覆盖右冠状动脉（RCA）；3）一个双斜薄层，覆盖LCX的近端和远端节段。全心数据集以相同方向重新格式化。分别确定并比较了每条血管的可见血管长度、血管清晰度和血管直径。全心冠状动脉MRA显示LM/LAD（11.7±3.4厘米）和LCX（6.9±3.6厘米）的可视距离明显长于横向容积（LM/LAD，6.1±1.1厘米，P<0.001；LCX，4.2±1.2厘米，P<0.05）。全心方法中RCA和LCX的可见血管长度相对于其各自目标容积的改善并不显著。结论是，全心冠状动脉MRA技术提高了可见血管长度，并有助于在单次测量中对完整冠状动脉树进行高质量的冠状动脉MRA检查。
