Jacobsen S, Jensen K E, Thomsen C, Danneskiold-Samsoe B, Henriksen O
Department of Rheumatology, Hvidovre Hospital, University of Copenhagen, Denmark.
J Rheumatol. 1992 Oct;19(10):1600-3.
31Phosphorous nuclear magnetic resonance (31P NMR) spectroscopy of painful calf muscle was performed in 12 patients with fibromyalgia (FS) and 7 healthy subjects during rest, aerobic and anaerobic exercising conditions, and postexercise recovery. Ratios of inorganic phosphate and creatinine phosphate (Pi/PCr) and pH were calculated from the collected 31P NMR spectra. Resting values of Pi/PCr were normal in the patients. Patients delivered only 49% of the muscle power of the controls (p = 0.005). Patients and controls had similar rates of Pi/PCr and pH changes during work and recovery. The controls were able to change their Pi/PCr and pH more than the patients, due to the greater workload reached. However, statistical significance was reached only for the anaerobic static exercise (p = 0.003). It was concluded that patients with FS have a reduced voluntary capacity for work, but normal biochemical response to work and recovery.
对12名纤维肌痛（FS）患者和7名健康受试者的疼痛小腿肌肉进行了31磷核磁共振（31P NMR）光谱分析，检测条件包括静息、有氧和无氧运动以及运动后恢复阶段。根据收集到的31P NMR光谱计算无机磷酸盐与磷酸肌酸（Pi/PCr）的比率以及pH值。患者静息时的Pi/PCr值正常。患者产生的肌肉力量仅为对照组的49%（p = 0.005）。患者和对照组在工作和恢复过程中Pi/PCr和pH值的变化速率相似。由于达到了更大的工作量，对照组比患者能够更大程度地改变其Pi/PCr和pH值。然而，仅在无氧静态运动时达到了统计学显著性（p = 0.003）。研究得出结论，FS患者的自愿工作能力降低，但对工作和恢复的生化反应正常。
