Neander K-D, Hesse F
German Research and Consulting Centre for Nursing Products, Göttingen, Germany.
J Wound Care. 2003 Nov;12(10):369-71. doi: 10.12968/jowc.2003.12.10.26548.
This study investigated the effect of Cavilon No Sting Barrier Film (NSBF) (3M Healthcare) on erythema on the edges of highly exuding wounds in patients with venous stasis ulcers.
An intra-individual double-blind randomised test was performed on 239 patients. The two sides of each wound on each patient were treated with two different dressings: Cavilon NSBF was applied to the wound edges of one side and a control (water) to the edges of the other. Erythema was assessed daily using a chromameter.
These are based on the 227 patients who completed the study. The researchers were surprised by their unambiguity: in 88.1% of patients, the erythema completely disappeared within three days of treatment with the test material; in the remaining 11.9% it had completely disappeared after four days. With the control, erythema intensity remained more or less unchanged throughout the four-day observation period.
This study demonstrates that Cavilon NSBF helped control erythema in all the patients: in 97.3% examined, the measurable and objectively recordable erythema receded within two days.
本研究调查了皮肤保护膜（NSBF）（3M医疗保健公司）对静脉淤滞性溃疡患者高度渗出性伤口边缘红斑的影响。
对239例患者进行个体内双盲随机试验。每位患者每个伤口的两侧分别用两种不同的敷料进行治疗：一侧伤口边缘涂抹皮肤保护膜NSBF，另一侧涂抹对照物（水）。每天使用色差计评估红斑情况。
这些结果基于227例完成研究的患者。研究人员对结果的明确性感到惊讶：在88.1%的患者中，使用测试材料治疗三天内红斑完全消失；其余11.9%的患者在四天后红斑完全消失。使用对照物时，在整个四天观察期内红斑强度基本保持不变。
本研究表明，皮肤保护膜NSBF有助于控制所有患者的红斑：在97.3%的受检患者中，可测量且可客观记录的红斑在两天内消退。
