Schuren Jan, Becker Anja, Sibbald R Gary
3M Germany Laboratory, Carl-Schurz-Strasse 1, 41453 Neuss, Germany.
Int Wound J. 2005 Sep;2(3):230-8. doi: 10.1111/j.1742-4801.2005.00131.x.
To undertake a systematic review of all reliable evaluations of the clinical performance and cost-effectiveness of a film-forming liquid acrylate in the protection of the chronic ulcer peri-wound skin. Results from searches were scrutinised by two reviewers to identify possible randomised controlled trials and full reports of these were obtained. Details of eligible studies were extracted and summarised independently by two reviewers using a data extraction sheet. Meta-analysis was used to combine the results of trials where the interventions and outcome measures were sufficiently similar. A total of nine eligible studies were identified. The review reveals that a liquid-film forming acrylate (Cavilon no-sting barrier film, 3M, Minneapolis, MN, USA) is a safe and effective skin barrier to protect the peri-wound area of chronic ulcers. There is no difference between the protective properties of different barrier methods that are used to protect the peri-wound skin around chronic ulcers. Compared with no treatment or a placebo, this liquid film-forming acrylate has a significant impact on the integrity of the peri-wound skin. In addition, it has significant benefits in terms of pain control and patient comfort, and its use may reduce nursing time.
对一种成膜液态丙烯酸酯在保护慢性溃疡伤口周围皮肤方面的临床性能和成本效益的所有可靠评估进行系统评价。两名评审员对检索结果进行审查，以确定可能的随机对照试验，并获取这些试验的完整报告。两名评审员使用数据提取表独立提取并总结符合条件的研究细节。当干预措施和结果测量足够相似时，采用荟萃分析来合并试验结果。共确定了9项符合条件的研究。该评价表明，一种成膜液态丙烯酸酯（美国明尼阿波利斯3M公司的Cavilon无刺痛屏障膜）是保护慢性溃疡伤口周围区域的一种安全有效的皮肤屏障。用于保护慢性溃疡周围伤口皮肤的不同屏障方法的保护特性之间没有差异。与不治疗或使用安慰剂相比，这种成膜液态丙烯酸酯对伤口周围皮肤的完整性有显著影响。此外，它在疼痛控制和患者舒适度方面有显著益处，并且其使用可能减少护理时间。
