3M Company, St. Paul, MN, USA.
Skin Res Technol. 2021 Sep;27(5):891-895. doi: 10.1111/srt.13038. Epub 2021 Mar 24.
Barrier films have been used for many years to protect skin from the damaging effects of excessive moisture and mechanical injury. The performance characteristics important for these protective effects are mainly product durability and its ability to reduce the force of adhesive removal. Additionally, the moisture vapor transmission rate through the film needs to be high enough that maceration is prevented. The current study was undertaken to investigate various physical performance characteristics of six commercially available barrier films.
Several bench tests were used to simulate performance features of the barriers on skin including barrier durability, breathability (moisture vapor permeability), and the effect on adhesive dressing force of removal.
Results indicated that barrier films did not perform equivalently. However, Cavilon™ No Sting Barrier Film (NSB) was shown to have significantly greater durability in the barrier integrity test than all other barriers tested and was tied for highest breathability and highest reduction in peel force from steel. No other tested barrier film performed as consistently across the different tests.
These results may provide mechanistic understanding of how barriers such as NSB may clinically assist with the prevention of adhesive- and moisture-related skin damage.
多年来,屏障膜一直被用于保护皮肤免受过度潮湿和机械损伤的有害影响。对于这些保护效果很重要的性能特点主要是产品耐用性及其降低胶揭除力的能力。此外,通过膜的水蒸气传输率需要足够高,以防止浸渍。本研究旨在研究六种市售屏障膜的各种物理性能特点。
使用了几种台架测试来模拟屏障在皮肤上的性能特征,包括屏障耐久性、透气性(水蒸气透过率)以及对去除粘性敷料力的影响。
结果表明,屏障膜的性能并不等同。然而,Cavilon™无刺痛屏障膜(NSB)在屏障完整性测试中的耐用性明显优于所有其他测试的屏障,透气性和对钢的剥离力的降低率最高。没有其他测试的屏障膜在不同的测试中表现一致。
这些结果可能为 NSB 等屏障如何在临床上帮助预防与粘性和水分有关的皮肤损伤提供机制上的理解。