Birkeland S A, Kristoffersen K
Clin Exp Immunol. 1977 Dec;30(3):408-12.
In vitro tests of cellular immune responses, using lymphocyte transformation tests and rosette tests for T and B lymphocytes, were studied in a cross-section analysis of a total of fifty-five patients in six groups (non-pregnant, 2--3 months pregnant, 4--5 months pregnant, 6--7 months pregnant, at parturition and 3 months after parturition). No pregnancy-related changes were found in the numbers of T, B or null cells, nor changes in PHA, PWM or MLC responses, but a significant reversible depression of the PPD response was found in the second half of pregnancy.
在一项横断面分析中,对六组共55名患者(未怀孕、怀孕2 - 3个月、怀孕4 - 5个月、怀孕6 - 7个月、分娩时和分娩后3个月)进行了细胞免疫反应的体外测试,采用淋巴细胞转化试验和T、B淋巴细胞的玫瑰花结试验。未发现T细胞、B细胞或裸细胞数量有与妊娠相关的变化,PHA、PWM或MLC反应也无变化,但在妊娠后半期发现PPD反应有显著的可逆性降低。