对人类进行环氧树脂低分子低聚物的斑贴试验。

Patch testing with low molecular oligomers of epoxy resins in humans.

作者信息

Fregert S, Thorgeirsson A

出版信息

Contact Dermatitis. 1977 Dec;3(6):301-3. doi: 10.1111/j.1600-0536.1977.tb03691.x.

DOI:10.1111/j.1600-0536.1977.tb03691.x

Abstract

Thirty-four patients sensitive to epoxy resin were patch tested with oligomers of epoxy resin. All reacted when tested with MW 340 oligomer. Twenty-three were tested with MW 624 and MW 908 oligomers and seven with MW 1192 oligomer; none reacted. Eight patients tested with commercial mixtures of epoxy resins with an average MW 1280 and MW 1850 reacted to these resin mixtures which contained the MW 340 oligomer. The MW 340 oligomer seems to be the main ingredient responsible for contact allergy to epoxy resins in humans.

摘要

34名对环氧树脂敏感的患者用环氧树脂低聚物进行了斑贴试验。用分子量为340的低聚物进行测试时，所有人都有反应。23人用分子量为624和908的低聚物进行测试，7人用分子量为1192的低聚物进行测试，无人有反应。8名用平均分子量为1280和1850的环氧树脂商业混合物进行测试的患者对这些含有分子量为340低聚物的树脂混合物有反应。分子量为340的低聚物似乎是导致人类对环氧树脂接触性过敏的主要成分。