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心肌梗死后创伤后应激障碍的轨迹:一项前瞻性研究。

Trajectories of posttraumatic stress disorder following myocardial infarction: a prospective study.

作者信息

Ginzburg Karni, Solomon Zahava, Koifman Bella, Keren Gad, Roth Arie, Kriwisky Michael, Kutz Ilan, David Daniel, Bleich Avi

机构信息

Bob Shapell School of Social Work, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Clin Psychiatry. 2003 Oct;64(10):1217-23. doi: 10.4088/jcp.v64n1012.

Abstract

BACKGROUND

This study examines the trajectories of posttraumatic stress disorder (PTSD) following myocardial infarction (MI). More specifically, it has 2 aims: (1) to examine whether the trajectory of PTSD is predicted by level of threat and the nature of initial reactions and (2) to examine the associations between the trajectory of PTSD and anxiety, somatization, health-related quality of life, and hospitalization 7 months following MI.

METHOD

116 MI patients were examined twice. At time 1, within a week of the patient's MI, acute stress disorder (ASD) was assessed and medical measures were obtained from patients' hospital records. At time 2, 7 months later, PTSD, anxiety, physical residuals, and health-related quality of life were assessed. Data were gathered in 1999.

RESULTS

Six percent of the respondents had both ASD and PTSD, 10% did not have ASD but did have PTSD, and 12% had ASD but not PTSD. The trajectory of PTSD was associated with severity of anxiety, somatic complaints, and health-related quality of life. In addition, while the severity of MI did not predict the trajectory of PTSD, the perceived severity did. Patients without PTSD but with prior ASD did not differ in their initial reactions from those without ASD.

CONCLUSION

These findings provide support for the considerable variability in the trajectory of the development of PTSD and suggest that although ASD is associated with subsequent PTSD, the predictive role of initial reactions is limited.

摘要

背景

本研究探讨心肌梗死(MI)后创伤后应激障碍(PTSD)的发展轨迹。更具体地说,它有两个目标:(1)研究PTSD的发展轨迹是否由威胁程度和初始反应的性质所预测;(2)研究PTSD发展轨迹与焦虑、躯体化、健康相关生活质量以及MI后7个月住院情况之间的关联。

方法

对116名MI患者进行了两次检查。在时间1,即患者MI后的一周内,评估急性应激障碍(ASD),并从患者的医院记录中获取医疗措施。在时间2,即7个月后,评估PTSD、焦虑、身体残留症状以及健康相关生活质量。数据收集于1999年。

结果

6%的受访者同时患有ASD和PTSD,10%没有ASD但患有PTSD,12%患有ASD但没有PTSD。PTSD的发展轨迹与焦虑、躯体主诉以及健康相关生活质量的严重程度相关。此外,虽然MI的严重程度不能预测PTSD的发展轨迹,但感知到的严重程度可以。没有PTSD但有先前ASD的患者与没有ASD的患者在初始反应上没有差异。

结论

这些发现支持了PTSD发展轨迹存在相当大的变异性,并表明虽然ASD与随后的PTSD相关,但初始反应的预测作用有限。

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