Silfvast Tom, Pettilä Ville
Department of Anaesthesia and Intensive Care Medicine, Meilahti Hospital, Helsinki University Central Hospital, P.O. Box 340, FIN-00029 Helsinki, Finland.
Resuscitation. 2003 Dec;59(3):285-90. doi: 10.1016/s0300-9572(03)00237-5.
The charts of all adult patients with accidental hypothermia who were admitted to a single academic hospital during a 10 year period were retrospectively retrieved. The aim was to identify factors associated with survival of those with hypothermic cardiac arrest. Of 75 admitted patients, 44 were found to be haemodynamically stable and not to require invasive rewarming measures. Of the remaining 31 patients, 23 were in refractory cardiac arrest due to primary hypothermia and rewarmed using cardiopulmonary bypass (CPB). The aetiology of hypothermia was immersion in cold water in 48%, exposure to cold environment in 39% and submersion in 13% of these patients. Their median age was 50 years, and 83% were males. The patients received a total of 70 min of conventional CPR before institution of CPB. Fourteen of these patients (61%) survived to discharge from hospital. Factors associated with survival were age (P=0.015), arterial pH (P=0.011), PaCO2 (P=0.003), and serum potassium (P=0.007). Logistic regression analysis showed that of the 23 patients, 22 could be correctly classified as survivor or nonsurvivor based on the level of serum potassium and arterial pCO2. It is concluded that patients with cardiac arrest due to primary hypothermia tolerate long periods of conventional CPR before institution of CPB. The possible predictive role of serum potassium and arterial pCO2 needs further evaluation.
回顾性检索了一家学术医院在10年期间收治的所有成年意外低温患者的病历。目的是确定与低温性心脏骤停患者生存相关的因素。在75例入院患者中,44例血流动力学稳定,无需进行侵入性复温措施。在其余31例患者中,23例因原发性低温导致顽固性心脏骤停,并采用体外循环(CPB)进行复温。这些患者中,48%的低温病因是 immersion in cold water,39%是 exposure to cold environment,13%是 submersion。他们的中位年龄为50岁,83%为男性。在进行CPB之前,这些患者共接受了70分钟的传统心肺复苏。其中14例患者(61%)存活出院。与生存相关的因素有年龄(P=0.015)、动脉pH值(P=0.011)、动脉血二氧化碳分压(P=0.003)和血清钾(P=0.007)。Logistic回归分析显示,在这23例患者中,根据血清钾水平和动脉血二氧化碳分压,22例可被正确分类为幸存者或非幸存者。结论是,原发性低温导致心脏骤停的患者在进行CPB之前能够耐受长时间的传统心肺复苏。血清钾和动脉血二氧化碳分压的可能预测作用需要进一步评估。 (注:immersion in cold water、exposure to cold environment、submersion未找到完全准确对应中文,保留英文表述)