Gerber T C, Erbel R, Görge G, Ge J, Rupprecht H J, Meyer J
2nd Medical Clinic, Mainz University, Germany.
Am J Cardiol. 1992 Dec 15;70(20):1546-54. doi: 10.1016/0002-9149(92)90455-8.
The aim of this study was the assessment and classification of the morphologic effects of percutaneous transluminal angioplasty (PTCA) by intravascular ultrasound (IU). Fifty-eight patients were examined immediately after PTCA with a 4.8Fr, 20 MHz rotational tip IU system. In 10 patients (17%), IU images could not be analyzed due to failure of the imaging system or poor image quality. In 48 patients (83%; 40 men and 8 women, aged 55 +/- 9 years), IU images of 48 PTCA segments, as well as 41 distal and 44 proximal sites, were analyzed. The left anterior descending artery was studied in 30 patients, the right coronary artery in 17 and the left main coronary artery in 1. Calcium was present in 32 of 48 PTCA segments (67%). Plaque morphology was concentric in 18 patients (38%) and eccentric in 30 (62%). Seven distinct morphologic patterns were observed. In concentric plaques, plaque compression without significant wall alterations (type 1) was found in 2 patients (4%), superficial tears within the plaque (type 2) in 1 (2%) and deep tears (type 3) in 8 (17%). Deep tearing associated with submedial or subintimal dissection (type 4) was found in 2 patients (4%). Dissection between plaque and vessel wall without noticeable intimal tearing (type 5) was the most common morphology (n = 15; 31%) and occurred in concentric and eccentric plaques. In eccentric plaques, no significant tearing of the plaque (type 6) was found in 6 patients (13%), and tearing of the plaque close to its base with dissection (type 7) in 14 (29%).(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在通过血管内超声(IU)评估经皮腔内血管成形术(PTCA)的形态学效应并进行分类。58例患者在PTCA术后立即使用4.8Fr、20MHz旋转探头IU系统进行检查。10例患者(17%)因成像系统故障或图像质量差而无法分析IU图像。48例患者(83%;40例男性和8例女性,年龄55±9岁)的48个PTCA节段以及41个远端和44个近端部位的IU图像进行了分析。30例患者研究了左前降支,17例研究了右冠状动脉,1例研究了左主冠状动脉。48个PTCA节段中有32个(67%)存在钙化。斑块形态在18例患者(38%)中为同心性,30例(62%)为偏心性。观察到7种不同的形态学模式。在同心斑块中,2例患者(4%)发现斑块压缩但无明显管壁改变(1型),1例(2%)发现斑块内浅表撕裂(2型),8例(17%)发现深层撕裂(3型)。2例患者(4%)发现与中膜下或内膜下剥离相关的深层撕裂(4型)。斑块与血管壁之间的剥离但无明显内膜撕裂(5型)是最常见的形态(n = 15;31%),发生在同心和偏心斑块中。在偏心斑块中,6例患者(13%)未发现斑块明显撕裂(6型),14例(29%)发现靠近斑块基部的撕裂并伴有剥离(7型)。(摘要截于250字)