模拟层状核中的巧合检测。
Modeling coincidence detection in nucleus laminaris.
作者信息
Grau-Serrat Victor, Carr Catherine E, Simon Jonathan Z
机构信息
Department of Electrical and Computer Engineering, University of Maryland, College Park, MD 20742, USA.
出版信息
Biol Cybern. 2003 Nov;89(5):388-96. doi: 10.1007/s00422-003-0444-4. Epub 2003 Nov 28.
Abstract
A biologically detailed model of the binaural avian nucleus laminaris is constructed, as a two-dimensional array of multicompartment, conductance-based neurons, along tonotopic and interaural time delay (ITD) axes. The model is based primarily on data from chick nucleus laminaris. Typical chick-like parameters perform ITD discrimination up to 2 kHz, and enhancements for barn owl perform ITD discrimination up to 6 kHz. The dendritic length gradient of NL is explained concisely. The response to binaural out-of-phase input is suppressed well below the response to monaural input (without any spontaneous activity on the opposite side), implicating active potassium channels as crucial to good ITD discrimination.
摘要
构建了一个双耳禽层状核的生物细节模型，该模型作为一个基于电导的多隔室神经元的二维阵列，沿着音频拓扑和双耳时间延迟（ITD）轴排列。该模型主要基于来自鸡层状核的数据。典型的类似鸡的参数可实现高达2 kHz的ITD辨别，而谷仓猫头鹰的增强参数可实现高达6 kHz的ITD辨别。简明地解释了层状核的树突长度梯度。对双耳异相输入的反应被抑制到远低于对单耳输入的反应（另一侧没有任何自发活动），这表明活性钾通道对良好的ITD辨别至关重要。
相似文献
1
Modeling coincidence detection in nucleus laminaris.模拟层状核中的巧合检测。
Biol Cybern. 2003 Nov;89(5):388-96. doi: 10.1007/s00422-003-0444-4. Epub 2003 Nov 28.
2
Change in the coding of interaural time difference along the tonotopic axis of the chicken nucleus laminaris.鸡层状核的音频拓扑轴上双耳时间差编码的变化。
Front Neural Circuits. 2015 Aug 20;9:43. doi: 10.3389/fncir.2015.00043. eCollection 2015.
3
Effect of GABA on the processing of interaural time differences in nucleus laminaris neurons in the chick.γ-氨基丁酸对雏鸡层状核神经元双耳时间差处理的影响。
Eur J Neurosci. 1998 Nov;10(11):3438-50. doi: 10.1046/j.1460-9568.1998.00353.x.
4
A circuit for detection of interaural time differences in the brain stem of the barn owl.一种用于检测仓鸮脑干中双耳时间差的电路。
J Neurosci. 1990 Oct;10(10):3227-46. doi: 10.1523/JNEUROSCI.10-10-03227.1990.
5
In vivo Recordings from Low-Frequency Nucleus Laminaris in the Barn Owl.仓鸮低频层状核的体内记录
Brain Behav Evol. 2015;85(4):271-86. doi: 10.1159/000433513. Epub 2015 Jul 15.
6
Tonotopic specialization of auditory coincidence detection in nucleus laminaris of the chick.鸡层状核中听觉符合检测的音频拓扑特化
J Neurosci. 2005 Feb 23;25(8):1924-34. doi: 10.1523/JNEUROSCI.4428-04.2005.
7
Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl.经验依赖性可塑性在Barn Owl 的核层中。
J Neurosci. 2024 Jan 3;44(1):e0940232023. doi: 10.1523/JNEUROSCI.0940-23.2023.
8
Cochlear and neural delays for coincidence detection in owls.猫头鹰用于重合检测的耳蜗和神经延迟。
J Neurosci. 2001 Dec 1;21(23):9455-9. doi: 10.1523/JNEUROSCI.21-23-09455.2001.
9
Structure and dynamics that specialize neurons for high-frequency coincidence detection in the barn owl nucleus laminaris.结构和动态使鸣禽脑层状核中的神经元专门用于高频巧合检测。
Biol Cybern. 2023 Apr;117(1-2):143-162. doi: 10.1007/s00422-023-00962-z. Epub 2023 May 2.
10
Maps of ITD in the nucleus laminaris of the barn owl.关于 barn owl 核层状结构内 ITD 的图谱。
Adv Exp Med Biol. 2013;787:215-22. doi: 10.1007/978-1-4614-1590-9_24.
引用本文的文献
1
Somatic Integration of Incoherent Dendritic Inputs in the Gerbil Medial Superior Olive.沙鼠内侧上橄榄核中不连贯树突输入的体细胞整合。
J Neurosci. 2023 May 31;43(22):4093-4109. doi: 10.1523/JNEUROSCI.2215-22.2023. Epub 2023 May 2.
2
Structure and dynamics that specialize neurons for high-frequency coincidence detection in the barn owl nucleus laminaris.结构和动态使鸣禽脑层状核中的神经元专门用于高频巧合检测。
Biol Cybern. 2023 Apr;117(1-2):143-162. doi: 10.1007/s00422-023-00962-z. Epub 2023 May 2.
3
Free-field evoked auditory brainstem responses in cochlear implant users.人工耳蜗植入者的自由声场诱发听觉脑干反应
Audiol Res. 2018 Dec 7;8(2):216. doi: 10.4081/audiores.2018.216. eCollection 2018 Oct 2.
4
Dynamics of synaptic extracellular field potentials in the nucleus laminaris of the barn owl.鸣禽中窝核的突触细胞外场电位动力学。
J Neurophysiol. 2019 Mar 1;121(3):1034-1047. doi: 10.1152/jn.00648.2017. Epub 2018 Dec 21.
5
Activity-dependent synaptic integration and modulation of bilateral excitatory inputs in an auditory coincidence detection circuit.活动依赖性突触整合和双侧兴奋性输入在听觉吻合检测电路中的调制。
J Physiol. 2018 May 15;596(10):1981-1997. doi: 10.1113/JP275735. Epub 2018 Apr 16.
6
Sound localization in the alligator.短吻鳄的声音定位
Hear Res. 2015 Nov;329:11-20. doi: 10.1016/j.heares.2015.05.009. Epub 2015 Jun 3.
7
Minimal conductance-based model of auditory coincidence detector neurons.听觉重合检测神经元的最小电导模型。
PLoS One. 2015 Apr 6;10(4):e0122796. doi: 10.1371/journal.pone.0122796. eCollection 2015.
8
Coincidence detection in the medial superior olive: mechanistic implications of an analysis of input spiking patterns.中脑上橄榄核中的巧合检测：对输入尖峰模式分析的机制意义。
Front Neural Circuits. 2014 May 1;8:42. doi: 10.3389/fncir.2014.00042. eCollection 2014.
9
Theoretical foundations of the sound analog membrane potential that underlies coincidence detection in the barn owl.理论基础是声音模拟膜电位，它是猫头鹰中符合检测的基础。
Front Comput Neurosci. 2013 Nov 8;7:151. doi: 10.3389/fncom.2013.00151. eCollection 2013.
10
Biophysical basis of the sound analog membrane potential that underlies coincidence detection in the barn owl.支持大角猫头鹰共位检测的声音模拟膜电位的生物物理基础。
Front Comput Neurosci. 2013 Nov 8;7:102. doi: 10.3389/fncom.2013.00102. eCollection 2013.
本文引用的文献
1
A place theory of sound localization.声音定位的地点理论。
J Comp Physiol Psychol. 1948 Feb;41(1):35-9. doi: 10.1037/h0061495.
2
Branching dendritic trees and motoneuron membrane resistivity.分支树突状结构与运动神经元膜电阻
Exp Neurol. 1959 Nov;1:491-527. doi: 10.1016/0014-4886(59)90046-9.
3
A quantitative description of membrane current and its application to conduction and excitation in nerve.膜电流的定量描述及其在神经传导和兴奋中的应用。
J Physiol. 1952 Aug;117(4):500-44. doi: 10.1113/jphysiol.1952.sp004764.
4
5
Synaptic depression in the localization of sound.声音定位中的突触抑制
Nature. 2003 Jan 2;421(6918):66-70. doi: 10.1038/nature01248.
6
Enhancement of signal-to-noise ratio and phase locking for small inputs by a low-threshold outward current in auditory neurons.听觉神经元中低阈值外向电流对小输入信号的信噪比增强及锁相作用。
J Neurosci. 2002 Dec 15;22(24):11019-25. doi: 10.1523/JNEUROSCI.22-24-11019.2002.
7
Precise inhibition is essential for microsecond interaural time difference coding.精确抑制对于微秒级耳间时间差编码至关重要。
Nature. 2002 May 30;417(6888):543-7. doi: 10.1038/417543a.
8
Development of membrane conductance improves coincidence detection in the nucleus laminaris of the chicken.膜电导的发展改善了鸡延髓层状核中的同时性检测。
J Physiol. 2002 Apr 15;540(Pt 2):529-42. doi: 10.1113/jphysiol.2001.013365.
9
Evolution and development of time coding systems.时间编码系统的演变与发展
Curr Opin Neurobiol. 2001 Dec;11(6):727-33. doi: 10.1016/s0959-4388(01)00276-8.
10
Cochlear and neural delays for coincidence detection in owls.猫头鹰用于重合检测的耳蜗和神经延迟。
J Neurosci. 2001 Dec 1;21(23):9455-9. doi: 10.1523/JNEUROSCI.21-23-09455.2001.
Zotero 插件