Hotopf Matthew, David Anthony S, Hull Lisa, Nikalaou Vasilis, Unwin Catherine, Wessely Simon
Gulf War Illnesses Research Unit, Department of Psychological Medicine, Guy's, King's, and St Thomas's School of Medicine, London SE5 8AZ.
BMJ. 2003 Dec 13;327(7428):1370. doi: 10.1136/bmj.327.7428.1370.
Firstly, to describe changes in the health of Gulf war veterans studied in a previous occupational cohort study and to compare outcome with comparable non-deployed military personnel. Secondly, to determine whether differences in prevalence between Gulf veterans and controls at follow up can be explained by greater persistence or greater incidence of disorders.
Occupational cohort study in the form of a postal survey.
Military personnel who served in the 1991 Persian Gulf war; personnel who served on peacekeeping duties to Bosnia; military personnel who were deployed elsewhere ("Era" controls). All participants had responded to a previous survey.
United Kingdom.
Self reported fatigue measured on the Chalder fatigue scale; psychological distress measured on the general health questionnaire, physical functioning and health perception on the SF-36; and a count of physical symptoms.
Gulf war veterans experienced a modest reduction in prevalence of fatigue (48.8% at stage 1, 43.4% at stage 2) and psychological distress (40.0% stage 1, 37.1% stage 2) but a slight worsening of physical functioning on the SF-36 (90.3 stage 1, 88.7 stage 2). Compared with the other cohorts Gulf veterans continued to experience poorer health on all outcomes, although physical functioning also declined in Bosnia veterans. Era controls showed both lower incidence of fatigue than Gulf veterans, and both comparison groups showed less persistence of fatigue compared with Gulf veterans.
Gulf war veterans remain a group with many symptoms of ill health. The excess of illness at follow up is explained by both higher incidence and greater persistence of symptoms.
首先,描述在先前一项职业队列研究中所研究的海湾战争退伍军人的健康变化,并将结果与未部署的可比军事人员进行比较。其次,确定在随访时海湾退伍军人与对照组之间患病率的差异是否可以用疾病的更高持续性或更高发病率来解释。
以邮寄调查形式进行的职业队列研究。
1991年波斯湾战争中的军事人员;在波斯尼亚执行维和任务的人员;部署在其他地方的军事人员(“时代”对照组)。所有参与者都对先前的一项调查做出了回应。
英国。
用查尔德疲劳量表测量的自我报告疲劳;用一般健康问卷测量的心理困扰;SF-36量表上的身体功能和健康感知;以及身体症状计数。
海湾战争退伍军人的疲劳患病率(第1阶段为48.8%,第2阶段为43.4%)和心理困扰患病率(第1阶段为40.0%,第2阶段为37.1%)略有下降,但SF-36量表上的身体功能略有恶化(第1阶段为90.3,第2阶段为88.7)。与其他队列相比,海湾退伍军人在所有结局方面的健康状况仍然较差,尽管波斯尼亚退伍军人的身体功能也有所下降。“时代”对照组的疲劳发病率低于海湾退伍军人,与海湾退伍军人相比,两个比较组的疲劳持续性都较低。
海湾战争退伍军人仍然是一群有许多健康不佳症状的人。随访时疾病过多是由症状的更高发病率和更高持续性共同导致的。