路易体病
Lewy body disease.
作者信息
Hansen L A, Galasko D
机构信息
Department of Neurosciences, University of California, San Diego.
出版信息
Curr Opin Neurol Neurosurg. 1992 Dec;5(6):889-94.
PMID:1467583
Abstract
Subsumed under the rubric of Lewy body disease are idiopathic Parkinson's disease (PD), pure diffuse Lewy body disease (DLBD), and, most commonly, combined brainstem and neocortical Lewy bodies with Alzheimer's disease (AD) pathology in a relatively early developmental stage. Clinical correlates are dementia with psychiatric and subcortical features plus mild extrapyramidal signs (EPS).
摘要
路易体病这一类别涵盖特发性帕金森病（PD）、单纯弥漫性路易体病（DLBD），最常见的是脑干和新皮质路易体合并处于相对早期发展阶段的阿尔茨海默病（AD）病理改变。临床相关表现为伴有精神症状和皮质下特征的痴呆以及轻度锥体外系症状（EPS）。
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