de Bruin V M, Lees A J, Daniel S E
Parkinson's Disease Society Brain Bank, Institute of Neurology, London, England.
Mov Disord. 1992 Oct;7(4):355-8. doi: 10.1002/mds.870070410.
A 67-year-old man with a family history of parkinsonism had visual complaints due to difficulty in convergence, which was followed 2 years later by development of bradykinesia and rigidity. The diagnosis of Steele-Richardson-Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.
一名有帕金森病家族史的67岁男性因集合困难出现视觉症状，2年后出现运动迟缓及强直。基于核上性凝视麻痹、运动迟缓、强直及对左旋多巴反应不佳，诊断为斯蒂尔-理查森-奥尔谢夫斯基综合征。然而，随后的神经病理学检查显示为弥漫性路易体病，未发现涉及皮质下或脑干结构的神经原纤维缠结。
