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Hembase：血液学和红细胞生物学的浏览器及基因组门户。

Hembase: browser and genome portal for hematology and erythroid biology.

作者信息

Goh Sung-Ho, Lee Y Terry, Bouffard Gerard G, Miller Jeffery L

机构信息

Laboratory of Chemical Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, MD 20892, USA.

出版信息

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D572-4. doi: 10.1093/nar/gkh129.

DOI:10.1093/nar/gkh129
PMID:14681483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC308863/
Abstract

Hembase (http://hembase.niddk.nih.gov) is an integrated browser and genome portal designed for web-based examination of the human erythroid transcriptome. To date, Hembase contains 15,752 entries from erythroblast Expressed Sequenced Tags (ESTs) and 380 referenced genes relevant for erythropoiesis. The database is organized to provide a cytogenetic band position, a unique name as well as a concise annotation for each entry. Search queries may be performed by name, keyword or cytogenetic location. Search results are linked to primary sequence data and three major human genome browsers for access to information considered current at the time of each search. Hembase provides interested scientists and clinical hematologists with a genome-based approach toward the study of erythroid biology.

摘要

血红蛋白数据库（http://hembase.niddk.nih.gov）是一个集成浏览器和基因组门户网站，旨在通过网络对人类红细胞转录组进行检查。截至目前，血红蛋白数据库包含来自成红细胞表达序列标签（EST）的15752条记录以及与红细胞生成相关的380个参考基因。该数据库的组织方式是为每个条目提供细胞遗传学带位置、唯一名称以及简要注释。搜索查询可以通过名称、关键词或细胞遗传学位置进行。搜索结果与原始序列数据以及三个主要的人类基因组浏览器相链接，以便获取每次搜索时被视为最新的信息。血红蛋白数据库为感兴趣的科学家和临床血液学家提供了一种基于基因组的方法来研究红细胞生物学。

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