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Matlystatins, new inhibitors of typeIV collagenases from Actinomadura atramentaria. I. Taxonomy, fermentation, isolation, and physico-chemical properties of matlystatin-group compounds.

作者信息

Ogita T, Sato A, Enokita R, Suzuki K, Ishii M, Negishi T, Okazaki T, Tamaki K, Tanzawa K

机构信息

Fermentation Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.

出版信息

J Antibiot (Tokyo). 1992 Nov;45(11):1723-32. doi: 10.7164/antibiotics.45.1723.

DOI:10.7164/antibiotics.45.1723
PMID:1468979
Abstract

During the course of a screening for inhibitors of typeIV collagenases, new metabolites, designated matlystatins, have been isolated from an actinomycete strain, which was identified as a strain of Actinomadura atramentaria. Matlystatins were composed of five congeners, which were separated and purified by n-butanol extraction and chromatography.

摘要

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